6SCG
Structure of AdhE form 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue NAD A 1001 |
| Chain | Residue |
| A | ASP487 |
| A | THR598 |
| A | THR601 |
| A | VAL610 |
| A | LEU638 |
| A | LEU646 |
| A | HIS727 |
| A | HOH1102 |
| A | HOH1188 |
| A | HOH1189 |
| A | HOH1234 |
| A | PHE489 |
| A | HOH1277 |
| A | HOH1285 |
| A | HOH1310 |
| A | ALA518 |
| A | ASP519 |
| A | GLY545 |
| A | GLY546 |
| A | SER547 |
| A | PRO548 |
| A | THR597 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 1002 |
| Chain | Residue |
| A | ARG572 |
| A | ARG577 |
| A | ARG579 |
| A | ILE580 |
| A | TYR581 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 1003 |
| Chain | Residue |
| A | ARG526 |
| A | THR564 |
| A | HIS565 |
| A | PHE566 |
| A | HOH1255 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1004 |
| Chain | Residue |
| A | ASP538 |
| A | GLY587 |
| A | VAL588 |
| A | LYS591 |
| A | HOH1315 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue FE A 1005 |
| Chain | Residue |
| A | ASP653 |
| A | HIS657 |
| A | HIS723 |
| A | HIS737 |
| A | HOH1105 |
| A | HOH1318 |
| site_id | AC6 |
| Number of Residues | 25 |
| Details | binding site for residue NAD B 1001 |
| Chain | Residue |
| B | ASP487 |
| B | PHE489 |
| B | GLY545 |
| B | GLY546 |
| B | SER547 |
| B | PRO548 |
| B | ASP550 |
| B | THR597 |
| B | THR598 |
| B | THR601 |
| B | PHE608 |
| B | ALA609 |
| B | VAL610 |
| B | LEU638 |
| B | LEU646 |
| B | HIS737 |
| B | HOH1111 |
| B | HOH1123 |
| B | HOH1206 |
| B | HOH1221 |
| B | HOH1247 |
| B | HOH1285 |
| B | HOH1293 |
| B | HOH1295 |
| B | HOH1319 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue MES B 1002 |
| Chain | Residue |
| B | PHE491 |
| B | ASP497 |
| B | LYS504 |
| B | PRO812 |
| B | GLU817 |
| B | HOH1172 |
| B | HOH1274 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 1003 |
| Chain | Residue |
| B | ARG526 |
| B | HIS565 |
| B | PHE566 |
| B | HOH1103 |
| B | HOH1129 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue FE B 1004 |
| Chain | Residue |
| B | ASP653 |
| B | HIS657 |
| B | HIS723 |
| B | HIS737 |
| B | HOH1110 |
| B | HOH1362 |
Functional Information from PROSITE/UniProt
| site_id | PS00060 |
| Number of Residues | 21 |
| Details | ADH_IRON_2 Iron-containing alcohol dehydrogenases signature 2. GvCHsmAHkLGSqfhIpHGlA |
| Chain | Residue | Details |
| A | GLY720-ALA740 |
| site_id | PS00913 |
| Number of Residues | 29 |
| Details | ADH_IRON_1 Iron-containing alcohol dehydrogenases signature 1. AIvDanlvmdmPkslcAfGglDAVthamE |
| Chain | Residue | Details |
| A | ALA632-GLU660 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32523125","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7BVP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32188856","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32523125","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6TQH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6TQM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
