Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | binding site for residue L0Z A 701 |
Chain | Residue |
A | LEU408 |
A | ASN479 |
A | GLY480 |
A | GLU488 |
A | ARG490 |
A | ASP521 |
A | ASN526 |
A | SER538 |
A | ASP539 |
A | VAL546 |
A | TYR551 |
A | PHE413 |
A | HOH844 |
A | HOH904 |
A | HOH943 |
A | VAL416 |
A | ALA428 |
A | LYS430 |
A | GLU475 |
A | TYR476 |
A | MET477 |
A | ALA478 |
site_id | AC2 |
Number of Residues | 20 |
Details | binding site for residue L0Z B 701 |
Chain | Residue |
B | LYS406 |
B | PHE413 |
B | VAL416 |
B | TYR418 |
B | ALA428 |
B | LYS430 |
B | GLU475 |
B | TYR476 |
B | MET477 |
B | ALA478 |
B | ASN479 |
B | GLY480 |
B | ASP521 |
B | ASN526 |
B | ASP539 |
B | VAL546 |
B | TYR551 |
B | HOH888 |
B | HOH960 |
B | HOH975 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 23 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGTGQFGVVKyGkwrgqyd...........VAIK |
Chain | Residue | Details |
A | LEU408-LYS430 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FLHrDLAARNCLV |
Chain | Residue | Details |
A | PHE517-VAL529 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP521 | |
B | ASP521 | |
Chain | Residue | Details |
A | LEU408 | |
A | LYS430 | |
B | LEU408 | |
B | LYS430 | |
Chain | Residue | Details |
A | THR474 | |
B | THR474 | |
Chain | Residue | Details |
A | LEU542 | |
B | LEU542 | |
Chain | Residue | Details |
A | TYR551 | |
B | TYR551 | |
Chain | Residue | Details |
A | SER604 | |
B | SER604 | |
Chain | Residue | Details |
A | TYR617 | |
B | TYR617 | |
Chain | Residue | Details |
A | SER623 | |
B | SER623 | |