6S8W
Aromatic aminotransferase AroH (Aro8) form Aspergillus fumigatus in complex with PLP (internal aldimine)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0008793 | molecular_function | aromatic-amino-acid:2-oxoglutarate transaminase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0008793 | molecular_function | aromatic-amino-acid:2-oxoglutarate transaminase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0008793 | molecular_function | aromatic-amino-acid:2-oxoglutarate transaminase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008483 | molecular_function | transaminase activity |
| D | 0008793 | molecular_function | aromatic-amino-acid:2-oxoglutarate transaminase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue PLP A 601 |
| Chain | Residue |
| A | GLY184 |
| A | SER345 |
| A | SER347 |
| A | LYS348 |
| A | ARG355 |
| B | TYR149 |
| B | GLN378 |
| A | SER185 |
| A | THR186 |
| A | PHE210 |
| A | ILE262 |
| A | ASN267 |
| A | ASP295 |
| A | PRO297 |
| A | TYR298 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 602 |
| Chain | Residue |
| A | LEU75 |
| A | GLY92 |
| A | GLY93 |
| B | PHE210 |
| B | ASN267 |
| B | ARG498 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue FMT D 601 |
| Chain | Residue |
| C | LEU75 |
| C | GLY92 |
| C | GLY93 |
| D | PHE210 |
| D | ASN267 |
| D | PHE442 |
| D | ARG498 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide PLP B 601 and LYS B 348 |
| Chain | Residue |
| A | TYR149 |
| A | GLN378 |
| B | GLY184 |
| B | SER185 |
| B | THR186 |
| B | PHE210 |
| B | ASN267 |
| B | ASP295 |
| B | PRO297 |
| B | TYR298 |
| B | SER345 |
| B | PHE346 |
| B | SER347 |
| B | VAL349 |
| B | ARG355 |
| B | MET441 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide PLP C 601 and LYS C 348 |
| Chain | Residue |
| C | GLY184 |
| C | SER185 |
| C | THR186 |
| C | PHE210 |
| C | ILE262 |
| C | ASN267 |
| C | ASP295 |
| C | PRO297 |
| C | TYR298 |
| C | SER345 |
| C | PHE346 |
| C | SER347 |
| C | VAL349 |
| C | ARG355 |
| D | TYR149 |
| D | GLN378 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide PLP D 602 and LYS D 348 |
| Chain | Residue |
| C | GLY93 |
| C | TYR149 |
| C | GLN378 |
| D | GLY184 |
| D | SER185 |
| D | THR186 |
| D | PHE210 |
| D | ASN267 |
| D | ASP295 |
| D | PRO297 |
| D | TYR298 |
| D | SER345 |
| D | PHE346 |
| D | SER347 |
| D | VAL349 |
| D | ARG355 |
Functional Information from PROSITE/UniProt
