6S87
Crystal structure of 2-methylcitrate synthase (PrpC) from Pseudomonas aeruginosa in complex with oxaloacetate.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0036440 | molecular_function | citrate synthase activity |
| A | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
| A | 0050440 | molecular_function | 2-methylcitrate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0036440 | molecular_function | citrate synthase activity |
| B | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
| B | 0050440 | molecular_function | 2-methylcitrate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0036440 | molecular_function | citrate synthase activity |
| C | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
| C | 0050440 | molecular_function | 2-methylcitrate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0036440 | molecular_function | citrate synthase activity |
| D | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
| D | 0050440 | molecular_function | 2-methylcitrate synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | GLY224 |
| A | ALA225 |
| A | ASN226 |
| A | ASP312 |
| A | THR330 |
| A | PHE333 |
| A | HOH502 |
| A | HOH530 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| B | GLN118 |
| B | ASP121 |
| B | GLU111 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | GLY224 |
| B | ALA225 |
| B | ASN226 |
| B | ASP312 |
| B | THR330 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 401 |
| Chain | Residue |
| C | GLY224 |
| C | ALA225 |
| C | ASN226 |
| C | ASP312 |
| C | THR330 |
| C | PHE333 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 401 |
| Chain | Residue |
| D | ARG139 |
| D | ASN150 |
| D | LEU163 |
| D | GLY166 |
| D | HOH571 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 402 |
| Chain | Residue |
| C | THR202 |
| C | ARG356 |
| C | HOH538 |
| D | ASN190 |
| D | ALA191 |
| D | HIS222 |
| D | OAA403 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue OAA D 403 |
| Chain | Residue |
| C | ARG356 |
| D | HIS187 |
| D | ASN190 |
| D | HIS222 |
| D | HIS261 |
| D | ARG270 |
| D | ARG337 |
| D | GOL402 |
Functional Information from PROSITE/UniProt
| site_id | PS00480 |
| Number of Residues | 13 |
| Details | CITRATE_SYNTHASE Citrate synthase signature. GFGHaIy.KdsDPR |
| Chain | Residue | Details |
| A | GLY258-ARG270 |
