6S7Q
Crystal structure of ergothioneine degrading enzyme Ergothionase from Treponema denticola in complex with desmethyl-ergothioneine sulfonic acid
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004397 | molecular_function | histidine ammonia-lyase activity |
A | 0006548 | biological_process | L-histidine catabolic process |
A | 0016841 | molecular_function | ammonia-lyase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004397 | molecular_function | histidine ammonia-lyase activity |
B | 0006548 | biological_process | L-histidine catabolic process |
B | 0016841 | molecular_function | ammonia-lyase activity |
C | 0003824 | molecular_function | catalytic activity |
C | 0004397 | molecular_function | histidine ammonia-lyase activity |
C | 0006548 | biological_process | L-histidine catabolic process |
C | 0016841 | molecular_function | ammonia-lyase activity |
D | 0003824 | molecular_function | catalytic activity |
D | 0004397 | molecular_function | histidine ammonia-lyase activity |
D | 0006548 | biological_process | L-histidine catabolic process |
D | 0016841 | molecular_function | ammonia-lyase activity |
E | 0003824 | molecular_function | catalytic activity |
E | 0004397 | molecular_function | histidine ammonia-lyase activity |
E | 0006548 | biological_process | L-histidine catabolic process |
E | 0016841 | molecular_function | ammonia-lyase activity |
F | 0003824 | molecular_function | catalytic activity |
F | 0004397 | molecular_function | histidine ammonia-lyase activity |
F | 0006548 | biological_process | L-histidine catabolic process |
F | 0016841 | molecular_function | ammonia-lyase activity |
G | 0003824 | molecular_function | catalytic activity |
G | 0004397 | molecular_function | histidine ammonia-lyase activity |
G | 0006548 | biological_process | L-histidine catabolic process |
G | 0016841 | molecular_function | ammonia-lyase activity |
H | 0003824 | molecular_function | catalytic activity |
H | 0004397 | molecular_function | histidine ammonia-lyase activity |
H | 0006548 | biological_process | L-histidine catabolic process |
H | 0016841 | molecular_function | ammonia-lyase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue KZ5 A 501 |
Chain | Residue |
A | TYR54 |
A | ALA408 |
A | GLU412 |
B | ARG281 |
D | GLY380 |
D | THR381 |
D | LYS384 |
A | VAL60 |
A | GLY61 |
A | HIS84 |
A | GLU143 |
A | ILE146 |
A | SER195 |
A | ASN311 |
A | PHE327 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue KZ5 C 502 |
Chain | Residue |
B | GLY380 |
B | THR381 |
B | LYS384 |
C | TYR54 |
C | VAL60 |
C | GLY61 |
C | HIS84 |
C | GLU143 |
C | ILE146 |
C | SER195 |
C | ASN311 |
C | ALA408 |
C | GLU412 |
D | ARG281 |
site_id | AC3 |
Number of Residues | 16 |
Details | binding site for residue KZ5 D 501 |
Chain | Residue |
A | GLY380 |
A | THR381 |
A | LYS384 |
C | ARG281 |
D | TYR54 |
D | VAL60 |
D | GLY61 |
D | HIS84 |
D | GLU143 |
D | ILE146 |
D | SER195 |
D | ASN311 |
D | PHE327 |
D | ALA408 |
D | GLU412 |
D | HOH606 |
site_id | AC4 |
Number of Residues | 13 |
Details | binding site for residue KZ5 F 501 |
Chain | Residue |
E | ARG281 |
F | TYR54 |
F | VAL60 |
F | GLY61 |
F | HIS84 |
F | GLU143 |
F | SER195 |
F | ASN311 |
F | ALA408 |
F | GLU412 |
G | GLY380 |
G | THR381 |
G | LYS384 |
site_id | AC5 |
Number of Residues | 14 |
Details | binding site for residue KZ5 G 501 |
Chain | Residue |
F | GLY380 |
F | THR381 |
F | LYS384 |
G | TYR54 |
G | VAL60 |
G | GLY61 |
G | HIS84 |
G | GLU143 |
G | ILE146 |
G | SER195 |
G | ASN311 |
G | PHE327 |
G | GLU412 |
H | ARG281 |
site_id | AC6 |
Number of Residues | 21 |
Details | binding site for Di-peptide KZ5 C 501 and LYS C 384 |
Chain | Residue |
A | ARG281 |
B | TYR54 |
B | VAL60 |
B | GLY61 |
B | HIS84 |
B | SER139 |
B | ILE141 |
B | GLU143 |
B | ILE146 |
B | SER195 |
B | ASN311 |
B | PHE327 |
B | ALA408 |
B | GLU412 |
C | GLY380 |
C | THR381 |
C | ILE382 |
C | GLN383 |
C | THR385 |
C | PHE386 |
C | MET388 |
site_id | AC7 |
Number of Residues | 19 |
Details | binding site for Di-peptide KZ5 E 501 and LYS E 384 |
Chain | Residue |
E | THR387 |
E | MET388 |
H | TYR54 |
H | VAL60 |
H | GLY61 |
H | HIS84 |
H | SER139 |
H | ILE146 |
H | THR147 |
H | SER195 |
H | ASN311 |
H | LEU407 |
H | GLU412 |
E | GLY380 |
E | THR381 |
E | ILE382 |
E | GLN383 |
E | THR385 |
E | PHE386 |
site_id | AC8 |
Number of Residues | 17 |
Details | binding site for Di-peptide KZ5 H 501 and LYS H 384 |
Chain | Residue |
E | TYR54 |
E | GLY61 |
E | HIS84 |
E | SER139 |
E | ILE141 |
E | GLU143 |
E | ILE146 |
E | ALA408 |
E | GLU412 |
F | ARG281 |
H | GLY380 |
H | THR381 |
H | ILE382 |
H | GLN383 |
H | THR385 |
H | PHE386 |
H | MET388 |