6S5N

Non-square conformations of KtrA E125Q mutant rings with bound ATP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006813	biological_process	potassium ion transport
A	0008324	molecular_function	monoatomic cation transmembrane transporter activity
A	0042802	molecular_function	identical protein binding
A	0098655	biological_process	monoatomic cation transmembrane transport
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006813	biological_process	potassium ion transport
B	0008324	molecular_function	monoatomic cation transmembrane transporter activity
B	0042802	molecular_function	identical protein binding
B	0098655	biological_process	monoatomic cation transmembrane transport
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0006813	biological_process	potassium ion transport
C	0008324	molecular_function	monoatomic cation transmembrane transporter activity
C	0042802	molecular_function	identical protein binding
C	0098655	biological_process	monoatomic cation transmembrane transport
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0006813	biological_process	potassium ion transport
D	0008324	molecular_function	monoatomic cation transmembrane transporter activity
D	0042802	molecular_function	identical protein binding
D	0098655	biological_process	monoatomic cation transmembrane transport
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0006813	biological_process	potassium ion transport
E	0008324	molecular_function	monoatomic cation transmembrane transporter activity
E	0042802	molecular_function	identical protein binding
E	0098655	biological_process	monoatomic cation transmembrane transport
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0006813	biological_process	potassium ion transport
F	0008324	molecular_function	monoatomic cation transmembrane transporter activity
F	0042802	molecular_function	identical protein binding
F	0098655	biological_process	monoatomic cation transmembrane transport
G	0005515	molecular_function	protein binding
G	0005886	cellular_component	plasma membrane
G	0006813	biological_process	potassium ion transport
G	0008324	molecular_function	monoatomic cation transmembrane transporter activity
G	0042802	molecular_function	identical protein binding
G	0098655	biological_process	monoatomic cation transmembrane transport
H	0005515	molecular_function	protein binding
H	0005886	cellular_component	plasma membrane
H	0006813	biological_process	potassium ion transport
H	0008324	molecular_function	monoatomic cation transmembrane transporter activity
H	0042802	molecular_function	identical protein binding
H	0098655	biological_process	monoatomic cation transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue ATP A 601

Chain	Residue
A	GLY13
A	ALA57
A	ALA77
A	ALA80
A	ALA84
A	LYS103
B	GLN125
A	GLY15
A	ARG16
A	PHE17
A	ASP36
A	ILE37
A	ASN38
A	LYS41
A	ALA55

---

site_id	AC2
Number of Residues	17
Details	binding site for residue ATP B 601

Chain	Residue
A	GLN125
B	GLY13
B	GLY15
B	ARG16
B	PHE17
B	ASP36
B	ILE37
B	LYS41
B	ALA55
B	ASN56
B	ALA57
B	ALA77
B	ILE78
B	GLY79
B	ALA80
B	ALA84
B	LYS103

---

site_id	AC3
Number of Residues	15
Details	binding site for residue ATP C 601

Chain	Residue
C	GLY13
C	GLY15
C	ARG16
C	PHE17
C	ASP36
C	ILE37
C	ASN38
C	LYS41
C	ALA57
C	THR58
C	ALA77
C	ILE78
C	ALA84
D	ARG16
D	GLN125

---

site_id	AC4
Number of Residues	17
Details	binding site for residue ATP D 601

Chain	Residue
C	GLN125
D	GLY13
D	GLY15
D	ARG16
D	PHE17
D	ASP36
D	ILE37
D	ASN38
D	LYS41
D	ALA55
D	ASN56
D	ALA57
D	THR58
D	ALA77
D	ILE78
D	ALA80
D	ALA84

---

site_id	AC5
Number of Residues	13
Details	binding site for residue ATP E 601

Chain	Residue
E	GLY13
E	GLY15
E	ARG16
E	PHE17
E	ASP36
E	ILE37
E	LYS41
E	ALA77
E	ILE78
E	ALA80
E	ALA84
E	LYS103
F	GLN125

---

site_id	AC6
Number of Residues	17
Details	binding site for residue ATP F 601

Chain	Residue
E	GLN125
F	GLY13
F	GLY15
F	ARG16
F	PHE17
F	ASP36
F	ILE37
F	LYS41
F	ALA55
F	ASN56
F	ALA57
F	ALA77
F	ILE78
F	GLY79
F	ALA80
F	ALA84
F	LYS103

---

site_id	AC7
Number of Residues	17
Details	binding site for residue ATP G 601

Chain	Residue
G	ILE37
G	ASN38
G	LYS41
G	ALA55
G	ASN56
G	ALA57
G	THR58
G	ALA77
G	ALA80
G	ALA84
G	LYS103
H	GLN125
G	GLY13
G	GLY15
G	ARG16
G	PHE17
G	ASP36

---

site_id	AC8
Number of Residues	14
Details	binding site for residue ATP H 601

Chain	Residue
G	GLN125
H	GLY13
H	LEU14
H	GLY15
H	ARG16
H	PHE17
H	ASP36
H	ILE37
H	LYS41
H	ALA77
H	ILE78
H	ALA80
H	ALA84
H	LYS103

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	BINDING: BINDING => ECO:0000269|PubMed:12086676, ECO:0000269|PubMed:16990138

Chain	Residue	Details
C	ARG16
C	ASP36
E	LYS103
E	HIS109
E	GLN125
F	ARG16
F	ASP36
F	ASN56
F	ILE78
F	LYS103
F	HIS109
F	GLN125
G	ARG16
G	ASP36
G	ASN56
G	ILE78
G	LYS103
G	HIS109
G	GLN125
H	ARG16
H	ASP36
H	ASN56
H	ILE78
H	LYS103
H	HIS109
H	GLN125
A	ARG16
A	ASP36
A	ASN56
A	ILE78
A	LYS103
A	HIS109
A	GLN125
B	ARG16
B	ASP36
B	ASN56
B	ILE78
B	LYS103
B	HIS109
B	GLN125
C	ASN56
C	ILE78
C	LYS103
C	HIS109
C	GLN125
D	ARG16
D	ASP36
D	ASN56
D	ILE78
D	LYS103
D	HIS109
D	GLN125
E	ARG16
E	ASP36
E	ASN56
E	ILE78

---