6S57

Crystal structure of human ATAD2 bromodomain in complex withN-(3-(azepan-1-ylsulfonyl)-4-methylphenyl)-2-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)acetamide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006325	biological_process	chromatin organization
A	0006355	biological_process	regulation of transcription, DNA-templated
A	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue EDO A 1201

Chain	Residue
A	GLU988
A	LEU1093
A	ASP1094
A	HOH1330
A	HOH1381

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site_id	AC2
Number of Residues	18
Details	binding site for residue KVT A 1202

Chain	Residue
A	PRO1012
A	VAL1013
A	ASP1014
A	TYR1021
A	MET1029
A	ILE1056
A	ALA1060
A	ASN1064
A	ILE1074
A	HOH1305
A	HOH1308
A	HOH1329
A	HOH1352
A	HOH1418
A	ARG1007
A	VAL1008
A	PHE1009
A	LYS1011

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site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 1203

Chain	Residue
A	ARG1077
A	HOH1324
A	HOH1351

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site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 A 1204

Chain	Residue
A	ARG987
A	ARG990
A	ARG994
A	ARG1067
A	ARG1072
A	HOH1309
A	HOH1406

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