6S56
Crystal structure of human ATAD2 bromodomain in complex with N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)-2-(2,5-dioxo-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalen]-1-yl)acetamide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006325 | biological_process | chromatin organization |
| A | 0006355 | biological_process | regulation of transcription, DNA-templated |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1201 |
| Chain | Residue |
| A | HIS998 |
| A | GLU1091 |
| A | GLU1092 |
| A | LEU1093 |
| A | ASP1094 |
| A | HOH1320 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1202 |
| Chain | Residue |
| A | ASP1094 |
| A | HOH1318 |
| A | HOH1365 |
| A | GLU988 |
| A | GLU1092 |
| A | LEU1093 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1203 |
| Chain | Residue |
| A | ARG1077 |
| A | HOH1335 |
| A | HOH1347 |
| A | HOH1369 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 1204 |
| Chain | Residue |
| A | ARG987 |
| A | ARG990 |
| A | ARG994 |
| A | ARG1067 |
| A | ARG1072 |
| A | HOH1309 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue KVZ A 1205 |
| Chain | Residue |
| A | VAL1008 |
| A | PHE1009 |
| A | LYS1011 |
| A | PRO1012 |
| A | VAL1013 |
| A | ASP1014 |
| A | GLU1017 |
| A | TYR1021 |
| A | MET1029 |
| A | ILE1056 |
| A | ALA1060 |
| A | ASN1064 |
| A | ILE1074 |
| A | HOH1348 |
| A | HOH1395 |
