Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6S4B

Crystal Structure of BRD4(1) bound to inhibitor BUX1 (8)

Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue BU3 A 301
ChainResidue
ATRP81
AASP145
AMET149
AKUH302

site_idAC2
Number of Residues15
Detailsbinding site for residue KUH A 302
ChainResidue
AGLN85
AVAL87
ALEU92
AASN117
ATYR139
AASN140
ABU3301
AHOH420
AHOH440
AHOH486
ALYS57
AARG58
AGLN59
ATRP81
APRO82

site_idAC3
Number of Residues6
Detailsbinding site for residue CA A 303
ChainResidue
AASN61
AGLN64
ATYR137
AASN140
AHOH428
AHOH466

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues60
DetailsBROMODOMAIN_1 Bromodomain signature. AwpFqqpvDavklnlpDYYkiIktpMdmgtIkkrlenny..Ywnaqeciqdfnt.MftNCyiY
ChainResidueDetails
AALA80-TYR139

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Acetylated histone binding => ECO:0000269|PubMed:22464331
ChainResidueDetails
AASN140

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS99

227344

PDB entries from 2024-11-13

PDB statisticsPDBj update infoContact PDBjnumon