6S29
Structure of fission yeast Mis16-Mis19 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000510 | molecular_function | H3-H4 histone complex chaperone activity |
| A | 0000775 | cellular_component | chromosome, centromeric region |
| A | 0000776 | cellular_component | kinetochore |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006325 | biological_process | chromatin organization |
| A | 0006338 | biological_process | chromatin remodeling |
| A | 0034080 | biological_process | CENP-A containing chromatin assembly |
| A | 0042393 | molecular_function | histone binding |
| A | 0098654 | cellular_component | CENP-A recruiting complex |
| A | 0140462 | biological_process | pericentric heterochromatin organization |
| A | 0140463 | molecular_function | chromatin-protein adaptor activity |
| C | 0000510 | molecular_function | H3-H4 histone complex chaperone activity |
| C | 0000775 | cellular_component | chromosome, centromeric region |
| C | 0000776 | cellular_component | kinetochore |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006325 | biological_process | chromatin organization |
| C | 0006338 | biological_process | chromatin remodeling |
| C | 0034080 | biological_process | CENP-A containing chromatin assembly |
| C | 0042393 | molecular_function | histone binding |
| C | 0098654 | cellular_component | CENP-A recruiting complex |
| C | 0140462 | biological_process | pericentric heterochromatin organization |
| C | 0140463 | molecular_function | chromatin-protein adaptor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue BR A 501 |
| Chain | Residue |
| A | TRP190 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 502 |
| Chain | Residue |
| A | ARG312 |
| B | LEU79 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue BR B 201 |
| Chain | Residue |
| B | ASN106 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue BR C 501 |
| Chain | Residue |
| C | TRP190 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue BR C 502 |
| Chain | Residue |
| C | ARG312 |
| D | LEU79 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue BR D 201 |
| Chain | Residue |
| D | ASN106 |
| D | HOH368 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LATGaeDqVICLWDV |
| Chain | Residue | Details |
| A | LEU198-VAL212 | |
| A | LEU297-LEU311 | |
| A | LEU341-LEU355 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"WD 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"WD 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"WD 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"WD 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Region: {"description":"Interaction with the histone H4 N-terminus","evidences":[{"source":"UniProtKB","id":"P39984","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for interaction with HAT1","evidences":[{"source":"UniProtKB","id":"P39984","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
