6S1R

Structure of fission yeast Mis16 bound to histone H4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000510	molecular_function	H3-H4 histone complex chaperone activity
A	0000775	cellular_component	chromosome, centromeric region
A	0000776	cellular_component	kinetochore
A	0000785	cellular_component	chromatin
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006338	biological_process	chromatin remodeling
A	0034080	biological_process	CENP-A containing chromatin assembly
A	0042393	molecular_function	histone binding
A	0098654	cellular_component	CENP-A recruiting complex
A	0140463	molecular_function	chromatin-protein adaptor activity
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0030527	molecular_function	structural constituent of chromatin
B	0046982	molecular_function	protein heterodimerization activity

Functional Information from PROSITE/UniProt

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
B	GLY15-HIS19

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site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LATGaeDqVICLWDV

Chain	Residue	Details
A	LEU198-VAL212
A	LEU297-LEU311
A	LEU341-LEU355

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	40
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	40
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	40
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	4
Details	Region: {"description":"Interaction with the histone H4 N-terminus","evidences":[{"source":"UniProtKB","id":"P39984","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Site: {"description":"Important for interaction with HAT1","evidences":[{"source":"UniProtKB","id":"P39984","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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