6S0R
The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus complex with nickel, sulfate and chloride
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 1901133 | biological_process | kanamycin biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 1901133 | biological_process | kanamycin biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| C | 0017000 | biological_process | antibiotic biosynthetic process |
| C | 1901133 | biological_process | kanamycin biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| D | 0017000 | biological_process | antibiotic biosynthetic process |
| D | 1901133 | biological_process | kanamycin biosynthetic process |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| E | 0017000 | biological_process | antibiotic biosynthetic process |
| E | 1901133 | biological_process | kanamycin biosynthetic process |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| F | 0017000 | biological_process | antibiotic biosynthetic process |
| F | 1901133 | biological_process | kanamycin biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NI A 301 |
| Chain | Residue |
| A | HIS132 |
| A | ASP134 |
| A | HIS219 |
| A | HOH406 |
| A | HOH462 |
| A | HOH465 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | GLY221 |
| A | ARG230 |
| A | HOH415 |
| A | HOH425 |
| A | HOH427 |
| A | HOH452 |
| A | HOH462 |
| A | ASN120 |
| A | GLN129 |
| A | THR165 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ARG86 |
| A | GLU87 |
| A | SER88 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ARG46 |
| A | THR47 |
| A | HOH434 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | LYS19 |
| A | ARG262 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue NI B 301 |
| Chain | Residue |
| B | HIS132 |
| B | ASP134 |
| B | HIS219 |
| B | HOH428 |
| B | HOH479 |
| B | HOH519 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | ASN120 |
| B | GLN129 |
| B | THR165 |
| B | GLY221 |
| B | ARG230 |
| B | HOH406 |
| B | HOH407 |
| B | HOH453 |
| B | HOH479 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | ARG86 |
| B | GLU87 |
| B | SER88 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 304 |
| Chain | Residue |
| B | PRO188 |
| B | ALA189 |
| E | GLY77 |
| E | HOH453 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue NI C 301 |
| Chain | Residue |
| C | HIS132 |
| C | ASP134 |
| C | HIS219 |
| C | HOH413 |
| C | HOH429 |
| C | HOH451 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 302 |
| Chain | Residue |
| C | ASN120 |
| C | THR165 |
| C | GLY221 |
| C | ARG230 |
| C | LEU232 |
| C | HOH408 |
| C | HOH413 |
| C | HOH426 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 303 |
| Chain | Residue |
| C | ARG86 |
| C | GLU87 |
| C | SER88 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 304 |
| Chain | Residue |
| C | GLU9 |
| C | ARG28 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue NI D 301 |
| Chain | Residue |
| D | HIS132 |
| D | ASP134 |
| D | HIS219 |
| D | HOH458 |
| D | HOH469 |
| D | HOH477 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 D 302 |
| Chain | Residue |
| D | ASN120 |
| D | THR165 |
| D | GLY221 |
| D | ARG230 |
| D | HOH414 |
| D | HOH432 |
| D | HOH466 |
| D | HOH469 |
| D | HOH470 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 303 |
| Chain | Residue |
| D | ARG86 |
| D | GLU87 |
| D | SER88 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 304 |
| Chain | Residue |
| D | GLU9 |
| D | ARG28 |
| D | HOH439 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 305 |
| Chain | Residue |
| D | ARG46 |
| D | THR47 |
| D | ARG48 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue NI E 301 |
| Chain | Residue |
| E | HIS132 |
| E | ASP134 |
| E | HIS219 |
| E | HOH406 |
| E | HOH423 |
| E | HOH433 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 E 302 |
| Chain | Residue |
| E | LEU232 |
| E | HOH406 |
| E | HOH411 |
| E | ASN120 |
| E | THR165 |
| E | GLY221 |
| E | ARG230 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 303 |
| Chain | Residue |
| E | ARG86 |
| E | GLU87 |
| E | SER88 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 E 304 |
| Chain | Residue |
| E | ARG46 |
| E | THR47 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue NI F 301 |
| Chain | Residue |
| F | HIS132 |
| F | ASP134 |
| F | HIS219 |
| F | HOH410 |
| F | HOH451 |
| F | HOH471 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 F 302 |
| Chain | Residue |
| F | ASN120 |
| F | THR165 |
| F | ARG230 |
| F | LEU232 |
| F | HOH410 |
| F | HOH418 |
| F | HOH425 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 303 |
| Chain | Residue |
| F | ARG86 |
| F | GLU87 |
| F | SER88 |
| site_id | AE8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 F 304 |
| Chain | Residue |
| F | LYS254 |
| F | HOH401 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 F 305 |
| Chain | Residue |
| F | GLU9 |
| F | ARG28 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 306 |
| Chain | Residue |
| F | ARG46 |
| F | THR47 |
| F | HOH407 |
