6S07
Structure of formylglycine-generating enzyme at 1.04 A in complex with copper and substrate reveals an acidic pocket for binding and acti-vation of molecular oxygen.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0018158 | biological_process | protein oxidation |
| A | 0043687 | biological_process | post-translational protein modification |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0120147 | molecular_function | formylglycine-generating oxidase activity |
| A | 1903136 | molecular_function | cuprous ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue CU1 A 401 |
| Chain | Residue |
| A | CYS269 |
| A | CYS274 |
| C | CYS7 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | ASN222 |
| A | VAL223 |
| A | GLY225 |
| A | VAL227 |
| A | GLU229 |
| A | GLY265 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ASN188 |
| A | ILE189 |
| A | ASP202 |
| A | TYR204 |
| A | HOH532 |
| A | HOH539 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | PRO131 |
| A | ASN132 |
| A | HIS133 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28544744, ECO:0007744|PDB:5NXL, ECO:0007744|PDB:5NYY |
| Chain | Residue | Details |
| A | ASN188 | |
| A | ILE189 | |
| A | ASP202 | |
| A | TYR204 | |
| A | ASN222 | |
| A | VAL223 | |
| A | GLY225 | |
| A | VAL227 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27862795, ECO:0000269|PubMed:28544744, ECO:0007744|PDB:5NXL, ECO:0007744|PDB:5NYY |
| Chain | Residue | Details |
| A | CYS269 | |
| A | CYS274 |
