Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue KNH A 201 |
| Chain | Residue |
| A | ASN52 |
| A | ILE131 |
| A | PHE132 |
| A | ASN133 |
| A | ASP136 |
| A | THR140 |
| A | OLC210 |
| A | ALA55 |
| A | ALA56 |
| A | TRP57 |
| A | ASN106 |
| A | ARG110 |
| A | VAL116 |
| A | ASP118 |
| A | PHE129 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue ZN A 202 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 203 |
| Chain | Residue |
| A | HIS-1 |
| A | HIS-1 |
| A | HIS2 |
| A | GLU39 |
| A | HIS43 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue OLC A 204 |
| Chain | Residue |
| A | ILE11 |
| A | OLC209 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue OLC A 205 |
| Chain | Residue |
| A | THR9 |
| A | LEU12 |
| A | OLC206 |
| A | SO4215 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue OLC A 206 |
| Chain | Residue |
| A | PHE6 |
| A | THR9 |
| A | OLC205 |
| A | OLC207 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue OLC A 207 |
| Chain | Residue |
| A | LEU90 |
| A | OLC206 |
| A | PEG213 |
| A | SO4217 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue OLC A 208 |
| Chain | Residue |
| A | TYR26 |
| A | PHE81 |
| A | ASP85 |
| A | OLC211 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue OLC A 209 |
| Chain | Residue |
| A | TYR5 |
| A | ALA14 |
| A | PHE82 |
| A | OLC204 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue OLC A 210 |
| Chain | Residue |
| A | PHE81 |
| A | ASP85 |
| A | KNH201 |
| A | OLC211 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue OLC A 211 |
| Chain | Residue |
| A | PHE81 |
| A | OLC208 |
| A | OLC210 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 213 |
| Chain | Residue |
| A | HIS-1 |
| A | GLU39 |
| A | PRO42 |
| A | OLC207 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 214 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 215 |
| Chain | Residue |
| A | LYS3 |
| A | PHE6 |
| A | ILE7 |
| A | GLY8 |
| A | THR9 |
| A | LYS63 |
| A | OLC205 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 216 |
| Chain | Residue |
| A | GLY62 |
| A | LYS63 |
| A | MET64 |
| A | THR65 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 217 |
| Chain | Residue |
| A | MET1 |
| A | HIS2 |
| A | LYS3 |
| A | OLC207 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 218 |
| Chain | Residue |
| A | LYS3 |
| A | LYS4 |
| A | TYR5 |
Functional Information from PROSITE/UniProt
| site_id | PS00855 |
| Number of Residues | 13 |
| Details | SPASE_II Signal peptidases II signature. LfAGALGNFIDRV |
| Chain | Residue | Details |
| A | LEU99-VAL111 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_00161","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00161","evidenceCode":"ECO:0000255"}]} |
