Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue OLC A 201 |
| Chain | Residue |
| A | VAL17 |
| A | VAL94 |
| A | LEU98 |
| A | ILE134 |
| A | SER137 |
| A | OLC202 |
| A | OLC204 |
| A | OLC205 |
| B | OLC101 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue OLC A 202 |
| Chain | Residue |
| A | LEU90 |
| A | PHE91 |
| A | VAL94 |
| A | OLC201 |
| A | 7PE215 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 203 |
| Chain | Residue |
| A | ALA14 |
| A | ILE19 |
| A | PHE82 |
| A | SER97 |
| A | PHE100 |
| A | 7PE214 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue OLC A 204 |
| Chain | Residue |
| A | THR9 |
| A | LEU12 |
| A | PHE16 |
| A | PHE20 |
| A | LEU60 |
| A | SER61 |
| A | PHE66 |
| A | OLC201 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue OLC A 205 |
| Chain | Residue |
| A | ILE28 |
| A | PHE38 |
| A | LEU45 |
| A | OLC201 |
| B | OLC101 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 206 |
| Chain | Residue |
| A | ILE83 |
| A | LYS84 |
| A | TYR127 |
| A | ASP128 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 207 |
| Chain | Residue |
| A | PHE129 |
| A | PRO130 |
| B | 7PE102 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 208 |
| Chain | Residue |
| A | SER37 |
| A | LYS152 |
| A | 7PE210 |
| A | 7PE216 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue 7PE A 209 |
| Chain | Residue |
| A | ILE74 |
| A | LEU78 |
| A | PHE81 |
| A | 7PE214 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue 7PE A 210 |
| Chain | Residue |
| A | PHE44 |
| A | ASN89 |
| A | ALA149 |
| A | GOL208 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue 7PE A 211 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue 7PE A 212 |
| Chain | Residue |
| A | ASP121 |
| A | TYR127 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue 7PE A 213 |
| Chain | Residue |
| A | LYS25 |
| A | ALA29 |
| A | ARG51 |
| A | THR113 |
| A | GLU115 |
| A | VAL117 |
| A | HOH301 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue 7PE A 214 |
| Chain | Residue |
| A | ILE19 |
| A | GLN22 |
| A | VAL23 |
| A | TYR26 |
| A | OLC203 |
| A | 7PE209 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue 7PE A 215 |
| Chain | Residue |
| A | HIS2 |
| A | ILE34 |
| A | PHE44 |
| A | TYR88 |
| A | LEU90 |
| A | PHE91 |
| A | OLC202 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue 7PE A 216 |
| Chain | Residue |
| A | VAL111 |
| A | LEU112 |
| A | LEU150 |
| A | LEU151 |
| A | LYS152 |
| A | THR154 |
| A | GOL208 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 217 |
| Chain | Residue |
| A | HIS0 |
| A | HIS2 |
| A | HIS43 |
| A | GLU115 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue 7PE A 218 |
| Chain | Residue |
| A | THR65 |
| A | PHE68 |
| A | GOL220 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 219 |
| Chain | Residue |
| A | GLY62 |
| A | LYS63 |
| A | MET64 |
| A | THR65 |
| A | GOL220 |
| A | HOH303 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 220 |
| Chain | Residue |
| A | HOH303 |
| A | THR65 |
| A | 7PE218 |
| A | GOL219 |
| site_id | AE3 |
| Number of Residues | 13 |
| Details | binding site for residue OLC B 101 |
| Chain | Residue |
| A | LEU45 |
| A | ASN52 |
| A | ASP118 |
| A | PHE129 |
| A | PRO130 |
| A | ILE131 |
| A | PHE132 |
| A | THR140 |
| A | OLC201 |
| A | OLC205 |
| B | IIL2 |
| B | SER3 |
| B | ALO4 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue 7PE B 102 |
| Chain | Residue |
| A | TRP57 |
| A | GOL207 |
| site_id | AE5 |
| Number of Residues | 19 |
| Details | binding site for Ligand residues ALO B 4 through SER B 3 bound to SER B 3 |
| Chain | Residue |
| A | GLY8 |
| A | LEU12 |
| A | ASN52 |
| A | GLY54 |
| A | TRP57 |
| A | LEU60 |
| A | PHE67 |
| A | THR71 |
| A | ILE74 |
| A | ASN106 |
| A | ARG110 |
| A | VAL116 |
| A | ASP118 |
| A | ASN133 |
| A | ASP136 |
| A | LEU139 |
| A | 7PE211 |
| A | HOH306 |
| B | OLC101 |
Functional Information from PROSITE/UniProt
| site_id | PS00855 |
| Number of Residues | 13 |
| Details | SPASE_II Signal peptidases II signature. LfAGALGNFIDRV |
| Chain | Residue | Details |
| A | LEU99-VAL111 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ILE11-THR31 | |
| A | LYS63-ILE83 | |
| A | TYR88-ILE108 | |
| A | ILE131-LEU151 | |
| Chain | Residue | Details |
| A | ASP118 | |
| A | ASP136 | |
