Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6RW5

Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF2 and IF3

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0003735	molecular_function	structural constituent of ribosome
0	0005739	cellular_component	mitochondrion
0	0005743	cellular_component	mitochondrial inner membrane
0	0005763	cellular_component	mitochondrial small ribosomal subunit
0	0005840	cellular_component	ribosome
0	0032543	biological_process	mitochondrial translation
0	1990904	cellular_component	ribonucleoprotein complex
1	0003723	molecular_function	RNA binding
1	0003735	molecular_function	structural constituent of ribosome
1	0005515	molecular_function	protein binding
1	0005739	cellular_component	mitochondrion
1	0005743	cellular_component	mitochondrial inner membrane
1	0005763	cellular_component	mitochondrial small ribosomal subunit
1	0005840	cellular_component	ribosome
1	0032543	biological_process	mitochondrial translation
1	1990904	cellular_component	ribonucleoprotein complex
2	0001650	cellular_component	fibrillar center
2	0003723	molecular_function	RNA binding
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005654	cellular_component	nucleoplasm
2	0005739	cellular_component	mitochondrion
2	0005743	cellular_component	mitochondrial inner membrane
2	0005761	cellular_component	mitochondrial ribosome
2	0005840	cellular_component	ribosome
2	0032543	biological_process	mitochondrial translation
2	1990904	cellular_component	ribonucleoprotein complex
3	0005515	molecular_function	protein binding
3	0005634	cellular_component	nucleus
3	0005654	cellular_component	nucleoplasm
3	0005739	cellular_component	mitochondrion
3	0005743	cellular_component	mitochondrial inner membrane
3	0005759	cellular_component	mitochondrial matrix
3	0005840	cellular_component	ribosome
3	0032543	biological_process	mitochondrial translation
3	0045862	biological_process	positive regulation of proteolysis
3	1990904	cellular_component	ribonucleoprotein complex
4	0003723	molecular_function	RNA binding
4	0005515	molecular_function	protein binding
4	0005739	cellular_component	mitochondrion
4	0005743	cellular_component	mitochondrial inner membrane
4	0005759	cellular_component	mitochondrial matrix
4	0005840	cellular_component	ribosome
4	0006417	biological_process	regulation of translation
4	0019843	molecular_function	rRNA binding
4	0032543	biological_process	mitochondrial translation
4	0043024	molecular_function	ribosomal small subunit binding
4	1990904	cellular_component	ribonucleoprotein complex
7	0000166	molecular_function	nucleotide binding
7	0001731	biological_process	formation of translation preinitiation complex
7	0003723	molecular_function	RNA binding
7	0003743	molecular_function	translation initiation factor activity
7	0003924	molecular_function	GTPase activity
7	0005525	molecular_function	GTP binding
7	0005737	cellular_component	cytoplasm
7	0005739	cellular_component	mitochondrion
7	0005759	cellular_component	mitochondrial matrix
7	0006412	biological_process	translation
7	0006413	biological_process	translational initiation
7	0008135	molecular_function	translation factor activity, RNA binding
7	0032790	biological_process	ribosome disassembly
7	0043024	molecular_function	ribosomal small subunit binding
7	0070013	cellular_component	intracellular organelle lumen
7	0070124	biological_process	mitochondrial translational initiation
8	0003743	molecular_function	translation initiation factor activity
8	0005515	molecular_function	protein binding
8	0005739	cellular_component	mitochondrion
8	0006412	biological_process	translation
8	0006413	biological_process	translational initiation
8	0008135	molecular_function	translation factor activity, RNA binding
8	0032790	biological_process	ribosome disassembly
8	0043022	molecular_function	ribosome binding
8	0043024	molecular_function	ribosomal small subunit binding
8	0070124	biological_process	mitochondrial translational initiation
B	0003735	molecular_function	structural constituent of ribosome
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005759	cellular_component	mitochondrial matrix
B	0005763	cellular_component	mitochondrial small ribosomal subunit
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0015935	cellular_component	small ribosomal subunit
B	0032543	biological_process	mitochondrial translation
B	0061668	biological_process	mitochondrial ribosome assembly
B	1990904	cellular_component	ribonucleoprotein complex
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005763	cellular_component	mitochondrial small ribosomal subunit
C	0005840	cellular_component	ribosome
C	0032543	biological_process	mitochondrial translation
C	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005763	cellular_component	mitochondrial small ribosomal subunit
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0032543	biological_process	mitochondrial translation
D	1990904	cellular_component	ribonucleoprotein complex
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005763	cellular_component	mitochondrial small ribosomal subunit
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0015935	cellular_component	small ribosomal subunit
E	0019843	molecular_function	rRNA binding
E	0032543	biological_process	mitochondrial translation
E	0070181	molecular_function	small ribosomal subunit rRNA binding
E	1990904	cellular_component	ribonucleoprotein complex
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005763	cellular_component	mitochondrial small ribosomal subunit
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
F	0032543	biological_process	mitochondrial translation
F	1990904	cellular_component	ribonucleoprotein complex
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005763	cellular_component	mitochondrial small ribosomal subunit
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0032543	biological_process	mitochondrial translation
G	0070013	cellular_component	intracellular organelle lumen
G	1990904	cellular_component	ribonucleoprotein complex
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005759	cellular_component	mitochondrial matrix
H	0005763	cellular_component	mitochondrial small ribosomal subunit
H	0005840	cellular_component	ribosome
H	0032543	biological_process	mitochondrial translation
H	1990904	cellular_component	ribonucleoprotein complex
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005763	cellular_component	mitochondrial small ribosomal subunit
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0032543	biological_process	mitochondrial translation
I	1990904	cellular_component	ribonucleoprotein complex
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0005761	cellular_component	mitochondrial ribosome
J	0005763	cellular_component	mitochondrial small ribosomal subunit
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	0032543	biological_process	mitochondrial translation
J	1990904	cellular_component	ribonucleoprotein complex
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005761	cellular_component	mitochondrial ribosome
K	0005763	cellular_component	mitochondrial small ribosomal subunit
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0032543	biological_process	mitochondrial translation
K	1990904	cellular_component	ribonucleoprotein complex
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005759	cellular_component	mitochondrial matrix
L	0005761	cellular_component	mitochondrial ribosome
L	0005763	cellular_component	mitochondrial small ribosomal subunit
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0032543	biological_process	mitochondrial translation
L	1990904	cellular_component	ribonucleoprotein complex
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005763	cellular_component	mitochondrial small ribosomal subunit
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0032543	biological_process	mitochondrial translation
M	1990904	cellular_component	ribonucleoprotein complex
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005763	cellular_component	mitochondrial small ribosomal subunit
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0019843	molecular_function	rRNA binding
N	0032543	biological_process	mitochondrial translation
N	1990904	cellular_component	ribonucleoprotein complex
O	0003735	molecular_function	structural constituent of ribosome
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0005763	cellular_component	mitochondrial small ribosomal subunit
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0032543	biological_process	mitochondrial translation
O	1990904	cellular_component	ribonucleoprotein complex
P	0003735	molecular_function	structural constituent of ribosome
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005763	cellular_component	mitochondrial small ribosomal subunit
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0032543	biological_process	mitochondrial translation
P	0070181	molecular_function	small ribosomal subunit rRNA binding
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005763	cellular_component	mitochondrial small ribosomal subunit
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0032543	biological_process	mitochondrial translation
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003735	molecular_function	structural constituent of ribosome
R	0005515	molecular_function	protein binding
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005761	cellular_component	mitochondrial ribosome
R	0005763	cellular_component	mitochondrial small ribosomal subunit
R	0005840	cellular_component	ribosome
R	0032543	biological_process	mitochondrial translation
R	1990904	cellular_component	ribonucleoprotein complex
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0032543	biological_process	mitochondrial translation
S	1990904	cellular_component	ribonucleoprotein complex
T	0003735	molecular_function	structural constituent of ribosome
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0005840	cellular_component	ribosome
T	0032543	biological_process	mitochondrial translation
T	1990904	cellular_component	ribonucleoprotein complex
U	0003723	molecular_function	RNA binding
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0005763	cellular_component	mitochondrial small ribosomal subunit
U	0005840	cellular_component	ribosome
U	0032543	biological_process	mitochondrial translation
U	1990904	cellular_component	ribonucleoprotein complex
V	0000049	molecular_function	tRNA binding
V	0003723	molecular_function	RNA binding
V	0005515	molecular_function	protein binding
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0005763	cellular_component	mitochondrial small ribosomal subunit
V	0005840	cellular_component	ribosome
V	0006417	biological_process	regulation of translation
V	0008283	biological_process	cell population proliferation
V	0019843	molecular_function	rRNA binding
V	0032543	biological_process	mitochondrial translation
V	1990904	cellular_component	ribonucleoprotein complex
W	0003723	molecular_function	RNA binding
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0005763	cellular_component	mitochondrial small ribosomal subunit
W	0005840	cellular_component	ribosome
W	0032543	biological_process	mitochondrial translation
W	1990904	cellular_component	ribonucleoprotein complex
X	0000166	molecular_function	nucleotide binding
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0003924	molecular_function	GTPase activity
X	0005515	molecular_function	protein binding
X	0005525	molecular_function	GTP binding
X	0005654	cellular_component	nucleoplasm
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0005759	cellular_component	mitochondrial matrix
X	0005761	cellular_component	mitochondrial ribosome
X	0005763	cellular_component	mitochondrial small ribosomal subunit
X	0005840	cellular_component	ribosome
X	0006915	biological_process	apoptotic process
X	0015935	cellular_component	small ribosomal subunit
X	0016787	molecular_function	hydrolase activity
X	0032543	biological_process	mitochondrial translation
X	0097190	biological_process	apoptotic signaling pathway
X	1990904	cellular_component	ribonucleoprotein complex
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005515	molecular_function	protein binding
Y	0005739	cellular_component	mitochondrion
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0005763	cellular_component	mitochondrial small ribosomal subunit
Y	0005840	cellular_component	ribosome
Y	0019904	molecular_function	protein domain specific binding
Y	0032543	biological_process	mitochondrial translation
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0005763	cellular_component	mitochondrial small ribosomal subunit
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0032543	biological_process	mitochondrial translation
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue NAD A 1701

Chain	Residue
A	A781
J	ARG38
L	LEU194
L	TYR195
L	TYR196
A	A782
A	A783
A	U948
A	U949
A	A1046
A	A1047
A	C1048
A	MG1736

site_id	AC2
Number of Residues	9
Details	binding site for residue SPM A 1702

Chain	Residue
A	U944
A	G945
A	U946
A	U1044
A	G1045
A	A1046
A	A1047
A	C1048
A	A1110

site_id	AC3
Number of Residues	11
Details	binding site for residue SRY A 1703

Chain	Residue
A	U655
A	U656
A	C898
A	G899
A	C1165
A	A1166
A	A1167
A	A1168
A	A1555
A	C1556
J	LYS71

site_id	AC4
Number of Residues	3
Details	binding site for residue MG A 1704

Chain	Residue
A	A718
A	G719
A	G791

site_id	AC5
Number of Residues	3
Details	binding site for residue MG A 1705

Chain	Residue
A	A938
A	A939
A	A940

site_id	AC6
Number of Residues	7
Details	binding site for residue MG A 1706

Chain	Residue
A	G1028
A	HOH1802
A	HOH1809
A	HOH1829
A	HOH1834
A	HOH1840
A	HOH1844

site_id	AC7
Number of Residues	5
Details	binding site for residue MG A 1707

Chain	Residue
A	A1054
A	HOH1813
A	HOH1837
A	HOH1838
A	HOH1841

site_id	AC8
Number of Residues	1
Details	binding site for residue MG A 1708

Chain	Residue
A	A1067

site_id	AC9
Number of Residues	4
Details	binding site for residue MG A 1709

Chain	Residue
A	C1070
A	A1082
A	HOH1801
A	HOH1822

site_id	AD1
Number of Residues	2
Details	binding site for residue MG A 1710

Chain	Residue
A	A1090
A	U1091

site_id	AD2
Number of Residues	3
Details	binding site for residue MG A 1711

Chain	Residue
A	U1259
A	G1327
A	G1328

site_id	AD3
Number of Residues	1
Details	binding site for residue MG A 1712

Chain	Residue
A	A1266

site_id	AD4
Number of Residues	4
Details	binding site for residue MG A 1713

Chain	Residue
A	A1434
A	HOH1814
A	HOH1818
A	HOH1846

site_id	AD5
Number of Residues	5
Details	binding site for residue MG A 1714

Chain	Residue
A	A1564
A	A1565
A	G1570
A	HOH1824
A	HOH1825

site_id	AD6
Number of Residues	6
Details	binding site for residue MG A 1715

Chain	Residue
A	A1565
A	G1570
A	A1572
A	A1573
A	HOH1810
A	HOH1811

site_id	AD7
Number of Residues	1
Details	binding site for residue MG A 1716

Chain	Residue
A	G1594

site_id	AD8
Number of Residues	5
Details	binding site for residue MG A 1717

Chain	Residue
A	G1045
A	HOH1821
A	HOH1827
A	HOH1833
A	HOH1836

site_id	AD9
Number of Residues	4
Details	binding site for residue MG A 1718

Chain	Residue
A	U947
A	G1045
A	HOH1819
A	HOH1830

site_id	AE1
Number of Residues	1
Details	binding site for residue MG A 1719

Chain	Residue
A	A1305

site_id	AE2
Number of Residues	3
Details	binding site for residue MG A 1720

Chain	Residue
A	U1255
A	G1345
A	HOH1820

site_id	AE3
Number of Residues	2
Details	binding site for residue MG A 1722

Chain	Residue
A	A801
A	C806

site_id	AE4
Number of Residues	2
Details	binding site for residue MG A 1723

Chain	Residue
A	C815
A	A816

site_id	AE5
Number of Residues	6
Details	binding site for residue MG A 1724

Chain	Residue
A	HOH1831
G	HIS51
A	G878
A	A881
A	A882
A	HOH1816

site_id	AE6
Number of Residues	1
Details	binding site for residue MG A 1725

Chain	Residue
A	A1318

site_id	AE7
Number of Residues	5
Details	binding site for residue MG A 1727

Chain	Residue
A	G653
A	U654
A	A663
A	G664
A	C665

site_id	AE8
Number of Residues	5
Details	binding site for residue MG A 1728

Chain	Residue
A	U674
A	U689
A	C828
A	HOH1807
A	HOH1842

site_id	AE9
Number of Residues	2
Details	binding site for residue MG A 1729

Chain	Residue
A	A731
A	A732

site_id	AF1
Number of Residues	2
Details	binding site for residue MG A 1730

Chain	Residue
A	A746
A	A747

site_id	AF2
Number of Residues	3
Details	binding site for residue MG A 1731

Chain	Residue
A	U758
A	C1146
A	HOH1839

site_id	AF3
Number of Residues	1
Details	binding site for residue MG A 1732

Chain	Residue
A	G820

site_id	AF4
Number of Residues	3
Details	binding site for residue MG A 1733

Chain	Residue
A	C898
A	HOH1817
A	HOH1823

site_id	AF5
Number of Residues	1
Details	binding site for residue MG A 1734

Chain	Residue
A	C908

site_id	AF6
Number of Residues	3
Details	binding site for residue MG A 1735

Chain	Residue
A	G676
A	G920
A	U921

site_id	AF7
Number of Residues	2
Details	binding site for residue MG A 1736

Chain	Residue
A	A1047
A	NAD1701

site_id	AF8
Number of Residues	1
Details	binding site for residue MG A 1738

Chain	Residue
A	G1092

site_id	AF9
Number of Residues	3
Details	binding site for residue MG A 1739

Chain	Residue
A	G943
A	A1102
A	A1104

site_id	AG1
Number of Residues	1
Details	binding site for residue MG A 1740

Chain	Residue
A	A1139

site_id	AG2
Number of Residues	4
Details	binding site for residue MG A 1741

Chain	Residue
A	C1143
A	HOH1812
A	HOH1832
A	HOH1845

site_id	AG3
Number of Residues	1
Details	binding site for residue MG A 1742

Chain	Residue
A	U1144

site_id	AG4
Number of Residues	1
Details	binding site for residue MG A 1744

Chain	Residue
A	U1208

site_id	AG5
Number of Residues	4
Details	binding site for residue MG A 1745

Chain	Residue
A	A1218
A	U1329
A	HOH1806
A	HOH1808

site_id	AG6
Number of Residues	4
Details	binding site for residue MG A 1746

Chain	Residue
A	HOH1803
A	HOH1805
A	HOH1815
K	HOH201

site_id	AG7
Number of Residues	3
Details	binding site for residue MG A 1747

Chain	Residue
A	C1233
A	C1234
A	U1235

site_id	AG8
Number of Residues	1
Details	binding site for residue MG A 1748

Chain	Residue
A	C1234

site_id	AG9
Number of Residues	2
Details	binding site for residue MG A 1749

Chain	Residue
A	U1259
A	G1327

site_id	AH1
Number of Residues	1
Details	binding site for residue MG A 1750

Chain	Residue
A	U1316

site_id	AH2
Number of Residues	1
Details	binding site for residue MG A 1751

Chain	Residue
A	G1412

site_id	AH3
Number of Residues	2
Details	binding site for residue MG A 1752

Chain	Residue
A	A1387
A	C1388

site_id	AH4
Number of Residues	1
Details	binding site for residue MG A 1753

Chain	Residue
A	G1401

site_id	AH5
Number of Residues	2
Details	binding site for residue MG A 1754

Chain	Residue
A	A1014
A	G1031

site_id	AH6
Number of Residues	1
Details	binding site for residue MG A 1755

Chain	Residue
A	A714

site_id	AH7
Number of Residues	1
Details	binding site for residue MG A 1757

Chain	Residue
A	G822

site_id	AH8
Number of Residues	1
Details	binding site for residue MG A 1758

Chain	Residue
A	A851

site_id	AH9
Number of Residues	2
Details	binding site for residue MG A 1759

Chain	Residue
A	G941
A	A942

site_id	AI1
Number of Residues	1
Details	binding site for residue MG A 1760

Chain	Residue
A	G857

site_id	AI2
Number of Residues	4
Details	binding site for residue K A 1761

Chain	Residue
A	C702
A	C707
A	C708
A	C842

site_id	AI3
Number of Residues	4
Details	binding site for residue K A 1762

Chain	Residue
A	G717
A	A718
A	G719
A	G791

site_id	AI4
Number of Residues	4
Details	binding site for residue K A 1763

Chain	Residue
A	C890
A	G901
J	PRO73
J	ASN74

site_id	AI5
Number of Residues	4
Details	binding site for residue K A 1764

Chain	Residue
A	C1105
A	U1107
A	U1592
A	U1593

site_id	AI6
Number of Residues	4
Details	binding site for residue K A 1765

Chain	Residue
A	A1198
A	G1199
A	G1200
A	G1421

site_id	AI7
Number of Residues	4
Details	binding site for residue K A 1766

Chain	Residue
A	A1198
A	G1199
A	G1361
A	G1362

site_id	AI8
Number of Residues	2
Details	binding site for residue K A 1767

Chain	Residue
A	G1199
A	G1200

site_id	AI9
Number of Residues	5
Details	binding site for residue K A 1768

Chain	Residue
A	A1256
A	U1257
A	C1330
A	U1335
A	G1336

site_id	AJ1
Number of Residues	3
Details	binding site for residue K A 1769

Chain	Residue
A	C1262
A	G1328
A	U1329

site_id	AJ2
Number of Residues	3
Details	binding site for residue K A 1770

Chain	Residue
A	C1330
A	G1334
A	U1335

site_id	AJ3
Number of Residues	2
Details	binding site for residue K A 1771

Chain	Residue
A	A1365
A	G1389

site_id	AJ4
Number of Residues	3
Details	binding site for residue K A 1772

Chain	Residue
A	G1176
A	G1476
A	U1477

site_id	AJ5
Number of Residues	4
Details	binding site for residue K A 1773

Chain	Residue
A	A1564
A	A1565
A	A1573
A	G1586

site_id	AJ6
Number of Residues	4
Details	binding site for residue K A 1774

Chain	Residue
A	G1489
A	U1490
A	C1491
A	U1560

site_id	AJ7
Number of Residues	4
Details	binding site for residue K A 1775

Chain	Residue
A	C800
A	A801
A	C805
A	C806

site_id	AJ8
Number of Residues	3
Details	binding site for residue K A 1776

Chain	Residue
A	C835
A	U838
A	U850

site_id	AJ9
Number of Residues	2
Details	binding site for residue K A 1777

Chain	Residue
A	U888
A	A905

site_id	AK1
Number of Residues	4
Details	binding site for residue MG B 301

Chain	Residue
B	HIS93
B	ASP224
B	ASP240
B	ASP241

site_id	AK2
Number of Residues	4
Details	binding site for residue ZN O 301

Chain	Residue
O	CYS94
O	CYS105
O	CYS108
O	CYS143

site_id	AK3
Number of Residues	4
Details	binding site for residue FES P 201

Chain	Residue
E	CYS105
P	CYS65
P	CYS68
P	CYS100

site_id	AK4
Number of Residues	5
Details	binding site for residue FES T 201

Chain	Residue
M	CYS26
M	ARG29
T	CYS139
T	CYS141
T	CYS149

site_id	AK5
Number of Residues	17
Details	binding site for residue ATP X 501

Chain	Residue
X	PRO84
X	LEU99
X	MET100
X	GLY131
X	THR132
X	GLY133
X	LYS134
X	THR135
X	LEU136
X	SER311
X	THR313
X	TYR348
X	PRO388
X	GLU392
X	MG502
X	HOH602
X	HOH603

site_id	AK6
Number of Residues	4
Details	binding site for residue MG X 502

Chain	Residue
X	THR135
X	ATP501
X	HOH602
X	HOH603

site_id	AK7
Number of Residues	9
Details	binding site for residue GNP X 503

Chain	Residue
X	TYR173
X	ARG177
X	TYR208
X	VAL209
X	ASP238
X	LYS245
X	HIS291
X	ASN292
X	LYS295

site_id	AK8
Number of Residues	1
Details	binding site for residue MG 3 201

Chain	Residue
3	ASN139

site_id	AK9
Number of Residues	20
Details	binding site for residue GNP 7 801

Chain	Residue
7	VAL189
7	ASP190
7	HIS191
7	GLY192
7	LYS193
7	THR194
7	THR195
7	GLY212
7	ILE213
7	THR214
7	GLY237
7	ASN288
7	LYS289
7	ASP291
7	SER324
7	ALA325
7	LEU326
7	MG802
7	HOH901
7	HOH902

site_id	AL1
Number of Residues	5
Details	binding site for residue MG 7 802

Chain	Residue
7	THR194
7	THR214
7	GNP801
7	HOH901
7	HOH902

site_id	AL2
Number of Residues	12
Details	binding site for residues MA6 A 1583 and MA6 A 1584

Chain	Residue
3	MET138
3	HIS141
3	LYS145
A	5MC1488
A	G1489
A	U1490
A	G1562
A	U1563
A	A1564
A	G1581
A	G1582
A	A1585

Functional Information from PROSITE/UniProt

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. MhGLimG.GLeVisitDnTPiPHN

Chain	Residue	Details
I	MET162-ASN184

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAnR

Chain	Residue	Details
J	LYS71-ARG78

site_id	PS00057
Number of Residues	25
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. VDYkn.VqlLsqFVSPftGCIygrHI

Chain	Residue	Details
P	VAL72-ILE96

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGrsAQagAirlAmAKAL

Chain	Residue	Details
G	GLY334-LEU352

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRkksIrVlvAVGNgk.GaAGfSigkat.DRmd.AF

Chain	Residue	Details
D	GLY236-PHE268

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VrSLFDARVHLG

Chain	Residue	Details
B	VAL81-GLY92

site_id	PS01176
Number of Residues	23
Details	IF2 Initiation factor 2 signature. GsLtsLKHhKddisiVktGmDCG

Chain	Residue	Details
7	GLY671-GLY693

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	64
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00268","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	9
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	80
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	68
Details	Repeat: {"description":"PPR 1"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	35
Details	Repeat: {"description":"PPR 2"}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	30
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25838379","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	10
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	64
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	42
Details	Domain: {"description":"CHCH","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	10
Details	Motif: {"description":"Cx9C motif 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	10
Details	Motif: {"description":"Cx9C motif 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	34
Details	Repeat: {"description":"PPR 3"}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	40
Details	Repeat: {"description":"PPR 4"}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	36
Details	Repeat: {"description":"PPR 5"}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	41
Details	Repeat: {"description":"PPR 6"}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	34
Details	Repeat: {"description":"PPR 7"}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	34
Details	Repeat: {"description":"PPR 8"}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	34
Details	Repeat: {"description":"PPR 9"}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	34
Details	Repeat: {"description":"PPR 10"}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	170
Details	Domain: {"description":"tr-type G"}

Chain

Residue

Details

site_id	SWS_FT_FI24
Number of Residues	7
Details	Region: {"description":"G1","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI25
Number of Residues	4
Details	Region: {"description":"G2","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI26
Number of Residues	3
Details	Region: {"description":"G3","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI27
Number of Residues	3
Details	Region: {"description":"G4","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI28
Number of Residues	2
Details	Region: {"description":"G5","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI29
Number of Residues	13
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI30
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q91YJ5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)