Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue NAD A 601 |
| Chain | Residue |
| A | ILE160 |
| A | GLY227 |
| A | GLU228 |
| A | THR242 |
| A | GLY243 |
| A | SER244 |
| A | MET247 |
| A | ALA250 |
| A | GLU265 |
| A | LEU266 |
| A | GLY267 |
| A | SER161 |
| A | CYS299 |
| A | GLU399 |
| A | PHE401 |
| A | PHE468 |
| A | HOH709 |
| A | HOH763 |
| A | HOH847 |
| A | HOH897 |
| A | ALA162 |
| A | PHE163 |
| A | ASN164 |
| A | LYS187 |
| A | SER189 |
| A | GLU190 |
| A | ALA224 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 602 |
| Chain | Residue |
| A | ASP412 |
| A | LEU413 |
| A | ARG441 |
| A | HOH725 |
| A | HOH727 |
| A | HOH743 |
| A | HOH791 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 603 |
| Chain | Residue |
| A | THR393 |
| A | ALA394 |
| A | ARG397 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 604 |
| Chain | Residue |
| A | GLN371 |
| A | ARG383 |
| A | HOH887 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 605 |
| Chain | Residue |
| A | ILE6 |
| A | GLY8 |
| A | ARG501 |
| A | THR503 |
| A | LEU504 |
| A | HOH721 |
| A | HOH735 |
| A | HOH746 |
| A | HOH755 |
| A | HOH861 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 606 |
| Chain | Residue |
| A | ARG142 |
| A | HOH875 |
| A | HOH918 |
| B | SER460 |
| B | ACT607 |
| B | HOH913 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 607 |
| Chain | Residue |
| A | ARG38 |
| A | GLY43 |
| A | ASN343 |
| A | GLU344 |
| A | ALA345 |
| A | HOH737 |
| A | HOH911 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 608 |
| Chain | Residue |
| A | GLU471 |
| A | LYS472 |
| A | HOH726 |
| A | HOH803 |
| A | HOH829 |
| B | LEU154 |
| B | ARG490 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 609 |
| Chain | Residue |
| A | SER277 |
| A | ALA434 |
| A | ASP435 |
| B | ASP435 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 610 |
| Chain | Residue |
| A | PHE165 |
| A | ARG298 |
| A | CYS299 |
| A | THR300 |
| site_id | AD2 |
| Number of Residues | 25 |
| Details | binding site for residue NAD B 601 |
| Chain | Residue |
| B | HOH712 |
| B | HOH810 |
| B | HOH818 |
| B | HOH906 |
| B | ILE160 |
| B | SER161 |
| B | ALA162 |
| B | PHE163 |
| B | ASN164 |
| B | LYS187 |
| B | SER189 |
| B | GLU190 |
| B | GLY227 |
| B | GLU228 |
| B | THR242 |
| B | GLY243 |
| B | SER244 |
| B | MET247 |
| B | GLU265 |
| B | LEU266 |
| B | GLY267 |
| B | CYS299 |
| B | GLU399 |
| B | PHE401 |
| B | PHE468 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 602 |
| Chain | Residue |
| B | ASP412 |
| B | LEU413 |
| B | ARG441 |
| B | HOH727 |
| B | HOH751 |
| B | HOH752 |
| B | HOH840 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 603 |
| Chain | Residue |
| B | THR393 |
| B | ALA394 |
| B | ARG397 |
| B | ARG418 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 604 |
| Chain | Residue |
| B | GLN371 |
| B | ARG383 |
| B | HOH703 |
| B | HOH761 |
| B | HOH837 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 605 |
| Chain | Residue |
| A | LEU154 |
| A | ARG490 |
| B | GLU471 |
| B | LYS472 |
| B | HOH747 |
| B | HOH827 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 606 |
| Chain | Residue |
| B | GLU118 |
| B | ALA462 |
| B | GLU463 |
| B | ILE464 |
| B | PHE468 |
| B | SER480 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 607 |
| Chain | Residue |
| A | SO4606 |
| A | HOH858 |
| B | ARG298 |
| B | HOH892 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue ACT B 608 |
| Chain | Residue |
| B | THR409 |
| B | ARG411 |
Functional Information from PROSITE/UniProt
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. LELGGNNA |
| Chain | Residue | Details |
| A | LEU264-ALA271 | |
