Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 27 |
Details | binding site for residue NAD A 601 |
Chain | Residue |
A | ILE160 |
A | GLY227 |
A | GLU228 |
A | THR242 |
A | GLY243 |
A | SER244 |
A | MET247 |
A | ALA250 |
A | GLU265 |
A | LEU266 |
A | GLY267 |
A | SER161 |
A | CYS299 |
A | GLU399 |
A | PHE401 |
A | PHE468 |
A | HOH709 |
A | HOH763 |
A | HOH847 |
A | HOH897 |
A | ALA162 |
A | PHE163 |
A | ASN164 |
A | LYS187 |
A | SER189 |
A | GLU190 |
A | ALA224 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue SO4 A 602 |
Chain | Residue |
A | ASP412 |
A | LEU413 |
A | ARG441 |
A | HOH725 |
A | HOH727 |
A | HOH743 |
A | HOH791 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 603 |
Chain | Residue |
A | THR393 |
A | ALA394 |
A | ARG397 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 604 |
Chain | Residue |
A | GLN371 |
A | ARG383 |
A | HOH887 |
site_id | AC5 |
Number of Residues | 10 |
Details | binding site for residue SO4 A 605 |
Chain | Residue |
A | ILE6 |
A | GLY8 |
A | ARG501 |
A | THR503 |
A | LEU504 |
A | HOH721 |
A | HOH735 |
A | HOH746 |
A | HOH755 |
A | HOH861 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 606 |
Chain | Residue |
A | ARG142 |
A | HOH875 |
A | HOH918 |
B | SER460 |
B | ACT607 |
B | HOH913 |
site_id | AC7 |
Number of Residues | 7 |
Details | binding site for residue GOL A 607 |
Chain | Residue |
A | ARG38 |
A | GLY43 |
A | ASN343 |
A | GLU344 |
A | ALA345 |
A | HOH737 |
A | HOH911 |
site_id | AC8 |
Number of Residues | 7 |
Details | binding site for residue GOL A 608 |
Chain | Residue |
A | GLU471 |
A | LYS472 |
A | HOH726 |
A | HOH803 |
A | HOH829 |
B | LEU154 |
B | ARG490 |
site_id | AC9 |
Number of Residues | 4 |
Details | binding site for residue GOL A 609 |
Chain | Residue |
A | SER277 |
A | ALA434 |
A | ASP435 |
B | ASP435 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue ACT A 610 |
Chain | Residue |
A | PHE165 |
A | ARG298 |
A | CYS299 |
A | THR300 |
site_id | AD2 |
Number of Residues | 25 |
Details | binding site for residue NAD B 601 |
Chain | Residue |
B | HOH712 |
B | HOH810 |
B | HOH818 |
B | HOH906 |
B | ILE160 |
B | SER161 |
B | ALA162 |
B | PHE163 |
B | ASN164 |
B | LYS187 |
B | SER189 |
B | GLU190 |
B | GLY227 |
B | GLU228 |
B | THR242 |
B | GLY243 |
B | SER244 |
B | MET247 |
B | GLU265 |
B | LEU266 |
B | GLY267 |
B | CYS299 |
B | GLU399 |
B | PHE401 |
B | PHE468 |
site_id | AD3 |
Number of Residues | 7 |
Details | binding site for residue SO4 B 602 |
Chain | Residue |
B | ASP412 |
B | LEU413 |
B | ARG441 |
B | HOH727 |
B | HOH751 |
B | HOH752 |
B | HOH840 |
site_id | AD4 |
Number of Residues | 4 |
Details | binding site for residue SO4 B 603 |
Chain | Residue |
B | THR393 |
B | ALA394 |
B | ARG397 |
B | ARG418 |
site_id | AD5 |
Number of Residues | 5 |
Details | binding site for residue SO4 B 604 |
Chain | Residue |
B | GLN371 |
B | ARG383 |
B | HOH703 |
B | HOH761 |
B | HOH837 |
site_id | AD6 |
Number of Residues | 6 |
Details | binding site for residue GOL B 605 |
Chain | Residue |
A | LEU154 |
A | ARG490 |
B | GLU471 |
B | LYS472 |
B | HOH747 |
B | HOH827 |
site_id | AD7 |
Number of Residues | 6 |
Details | binding site for residue GOL B 606 |
Chain | Residue |
B | GLU118 |
B | ALA462 |
B | GLU463 |
B | ILE464 |
B | PHE468 |
B | SER480 |
site_id | AD8 |
Number of Residues | 4 |
Details | binding site for residue ACT B 607 |
Chain | Residue |
A | SO4606 |
A | HOH858 |
B | ARG298 |
B | HOH892 |
site_id | AD9 |
Number of Residues | 2 |
Details | binding site for residue ACT B 608 |
Chain | Residue |
B | THR409 |
B | ARG411 |
Functional Information from PROSITE/UniProt
site_id | PS00687 |
Number of Residues | 8 |
Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. LELGGNNA |
Chain | Residue | Details |
A | LEU264-ALA271 | |