6RTD
Dihydro-heme d1 dehydrogenase NirN in complex with DHE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006783 | biological_process | heme biosynthetic process |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0006783 | biological_process | heme biosynthetic process |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue BU3 A 501 |
| Chain | Residue |
| A | ASP214 |
| A | HOH611 |
| A | HOH630 |
| B | TRP199 |
| B | ASP214 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue DHE A 502 |
| Chain | Residue |
| A | ARG164 |
| A | ARG189 |
| A | ASN190 |
| A | HIS323 |
| A | PHE369 |
| A | PHE370 |
| A | ARG372 |
| A | HIS417 |
| A | TRP432 |
| A | TYR461 |
| A | HOH659 |
| A | ARG36 |
| A | HIS147 |
| A | GLY149 |
| A | LYS151 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue HEC A 503 |
| Chain | Residue |
| A | HIS12 |
| A | CYS13 |
| A | CYS16 |
| A | HIS17 |
| A | PRO27 |
| A | LEU29 |
| A | LEU34 |
| A | ILE46 |
| A | ARG50 |
| A | THR53 |
| A | GLN54 |
| A | MET55 |
| A | PHE58 |
| A | TYR144 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue DHE B 501 |
| Chain | Residue |
| B | ARG36 |
| B | HIS147 |
| B | GLY148 |
| B | GLY149 |
| B | LYS151 |
| B | ARG164 |
| B | ARG189 |
| B | ASN190 |
| B | TYR240 |
| B | HIS323 |
| B | PHE369 |
| B | PHE370 |
| B | ARG372 |
| B | HIS417 |
| B | TYR461 |
| B | HOH601 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide HEC B 502 and CYS B 16 |
| Chain | Residue |
| B | HIS12 |
| B | CYS13 |
| B | GLN14 |
| B | ALA15 |
| B | HIS17 |
| B | GLY18 |
| B | GLY24 |
| B | SER25 |
| B | GLY26 |
| B | PRO27 |
| B | LEU29 |
| B | ILE46 |
| B | ARG50 |
| B | THR53 |
| B | GLN54 |
| B | MET55 |
| B | PHE58 |
| B | TYR144 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide HEC B 502 and CYS B 13 |
| Chain | Residue |
| B | TYR9 |
| B | HIS12 |
| B | GLN14 |
| B | ALA15 |
| B | CYS16 |
| B | HIS17 |
| B | PRO27 |
| B | LEU29 |
| B | ILE46 |
| B | ARG50 |
| B | THR53 |
| B | GLN54 |
| B | MET55 |
| B | PHE58 |
| B | TYR144 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: covalent => ECO:0000255|PROSITE-ProRule:PRU00433, ECO:0000269|PubMed:31173777, ECO:0007744|PDB:6RTD, ECO:0007744|PDB:6RTE |
| Chain | Residue | Details |
| A | CYS13 | |
| A | CYS16 | |
| B | CYS13 | |
| B | CYS16 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue => ECO:0000255|PROSITE-ProRule:PRU00433, ECO:0000269|PubMed:31173777, ECO:0007744|PDB:6RTD, ECO:0007744|PDB:6RTE |
| Chain | Residue | Details |
| A | HIS17 | |
| B | HIS17 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31173777, ECO:0007744|PDB:6RTD, ECO:0007744|PDB:6RTE |
| Chain | Residue | Details |
| A | ARG50 | |
| B | ARG50 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue => ECO:0000269|PubMed:31173777, ECO:0007744|PDB:6RTD, ECO:0007744|PDB:6RTE |
| Chain | Residue | Details |
| A | MET55 | |
| B | MET55 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: proximal binding residue => ECO:0000269|PubMed:31173777, ECO:0007744|PDB:6RTD |
| Chain | Residue | Details |
| A | HIS147 | |
| B | HIS147 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31173777, ECO:0007744|PDB:6RTD |
| Chain | Residue | Details |
| A | GLY149 | |
| B | ARG164 | |
| B | ARG189 | |
| B | ASN190 | |
| B | ARG372 | |
| B | HIS417 | |
| A | LYS151 | |
| A | ARG164 | |
| A | ARG189 | |
| A | ASN190 | |
| A | ARG372 | |
| A | HIS417 | |
| B | GLY149 | |
| B | LYS151 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | BINDING: distal binding residue => ECO:0000269|PubMed:31173777, ECO:0007744|PDB:6RTD |
| Chain | Residue | Details |
| A | HIS323 | |
| B | HIS323 |
