6RT6
The YTH domain of YTHDC1 protein in complex with GGm6AC oligonucleotide
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 601 |
| Chain | Residue |
| B | GLY344 |
| B | SER346 |
| B | LYS347 |
| B | HOH704 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 601 |
| Chain | Residue |
| C | HOH787 |
| C | ARG451 |
| C | GLU452 |
| C | HOH720 |
| C | HOH721 |
| C | HOH737 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 602 |
| Chain | Residue |
| B | LYS386 |
| B | GLN478 |
| B | GLU479 |
| C | GLY344 |
| C | LYS347 |
| C | HOH761 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 603 |
| Chain | Residue |
| C | SER419 |
| C | HIS420 |
| C | HIS421 |
| C | ARG451 |
| C | HOH709 |
| C | HOH712 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for Di-nucleotide 6MZ E 1 and C E 2 |
| Chain | Residue |
| B | LYS361 |
| B | SER362 |
| B | ASN363 |
| B | ASN367 |
| B | TRP377 |
| B | SER378 |
| B | TRP428 |
| B | LEU439 |
| B | ILE473 |
| B | GLY474 |
| B | ARG475 |
| B | ASP476 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31670957, ECO:0007744|PDB:6RT4, ECO:0007744|PDB:6RT5, ECO:0007744|PDB:6RT6, ECO:0007744|PDB:6RT7 |
| Chain | Residue | Details |
| B | LYS361 | |
| B | ASP476 | |
| C | LYS361 | |
| C | ASP476 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25242552, ECO:0000269|PubMed:31670957, ECO:0007744|PDB:6RT4, ECO:0007744|PDB:6RT5, ECO:0007744|PDB:6RT6, ECO:0007744|PDB:6RT7 |
| Chain | Residue | Details |
| B | TRP377 | |
| C | TRP377 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25242552 |
| Chain | Residue | Details |
| B | TRP428 | |
| C | TRP428 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| B | SER424 | |
| C | SER424 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| B | SER435 | |
| C | SER435 |
