Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005829 | cellular_component | cytosol |
| A | 0009820 | biological_process | alkaloid metabolic process |
| A | 0009821 | biological_process | alkaloid biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0035834 | biological_process | indole alkaloid metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005829 | cellular_component | cytosol |
| B | 0009820 | biological_process | alkaloid metabolic process |
| B | 0009821 | biological_process | alkaloid biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0035834 | biological_process | indole alkaloid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | GLY81 |
| A | SER170 |
| A | THR171 |
| A | TYR204 |
| A | HOH505 |
| A | HOH697 |
| A | HOH733 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | LYS89 |
| A | EDO403 |
| A | HOH587 |
| A | SER28 |
| A | GLU85 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | TYR31 |
| A | SER86 |
| A | LYS89 |
| A | EDO402 |
| A | HOH720 |
| A | HOH729 |
| B | TYR31 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | HIS137 |
| A | VAL138 |
| A | GLY139 |
| A | LEU140 |
| A | ILE156 |
| A | PHE161 |
| A | HOH510 |
| A | HOH702 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | LEU206 |
| A | ILE207 |
| A | ARG208 |
| A | ARG222 |
| A | ASN236 |
| A | ASP237 |
| A | HOH633 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | GLU129 |
| A | GLN132 |
| A | TRP133 |
| A | SER136 |
| A | LYS151 |
| A | HOH507 |
| A | HOH521 |
| A | HOH522 |
| A | HOH537 |
| A | HOH547 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| B | GLY81 |
| B | SER170 |
| B | THR171 |
| B | TYR202 |
| B | TYR204 |
| B | TYR221 |
| B | TYR224 |
| B | HOH509 |
| B | HOH556 |
| B | HOH565 |
| B | HOH632 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| A | PRO30 |
| A | TYR31 |
| A | HOH729 |
| B | LYS89 |
| B | HOH569 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| B | HIS137 |
| B | VAL138 |
| B | GLY139 |
| B | LEU140 |
| B | PHE161 |
| B | HOH547 |
| B | HOH715 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | ARG25 |
| B | SER86 |
| B | LYS89 |
| B | HOH520 |
| B | HOH607 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | GLU129 |
| B | GLN132 |
| B | TRP133 |
| B | SER136 |
| B | LYS151 |
| B | HOH506 |
| B | HOH511 |
| B | HOH527 |
| B | HOH528 |
| B | HOH553 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Motif: {"description":"Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole","evidences":[{"source":"UniProtKB","id":"Q5NUF3","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"32066966","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"32066966","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"32066966","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"A0A2P1GIW2","evidenceCode":"ECO:0000250"}]} |
