English 日本語简体中文繁體中文 한국어

✖

Menu

RCSB PDB PDBe BMRB Adv. Search Search help

Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6RP1

1.49 A RESOLUTION OF SPOROSARCINA PASTEURII UREASE INHIBITED IN THE PRESENCE OF NBPTO AT pH 6.5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0009039	molecular_function	urease activity
A	0016151	molecular_function	nickel cation binding
A	0016787	molecular_function	hydrolase activity
A	0019627	biological_process	urea metabolic process
A	0043419	biological_process	urea catabolic process
B	0005737	cellular_component	cytoplasm
B	0009039	molecular_function	urease activity
B	0016787	molecular_function	hydrolase activity
B	0035550	cellular_component	urease complex
B	0043419	biological_process	urea catabolic process
C	0005737	cellular_component	cytoplasm
C	0009039	molecular_function	urease activity
C	0016151	molecular_function	nickel cation binding
C	0016787	molecular_function	hydrolase activity
C	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
C	0043419	biological_process	urea catabolic process
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue EDO A 201

Chain	Residue
A	GLY50
C	LYS559
A	LYS51
A	THR52
A	PHE86
A	ASP88
A	HOH309
A	HOH343
C	VAL309
C	ASN310

site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 202

Chain	Residue
A	GLY27
A	LYS29
A	ASP67
A	ASP68
A	HOH302
A	HOH305

site_id	AC3
Number of Residues	6
Details	binding site for residue EDO A 203

Chain	Residue
A	CXM1
A	TYR32
A	ASP79
A	HOH301
A	HOH303
C	GLN472

site_id	AC4
Number of Residues	2
Details	binding site for residue SO4 B 201

Chain	Residue
B	ARG116
B	HOH374

site_id	AC5
Number of Residues	6
Details	binding site for residue NI C 601

Chain	Residue
C	KCX220
C	HIS222
C	HIS249
C	HIS275
C	GLY280
C	2PA619

site_id	AC6
Number of Residues	5
Details	binding site for residue NI C 602

Chain	Residue
C	HIS137
C	HIS139
C	KCX220
C	ASP363
C	2PA619

site_id	AC7
Number of Residues	6
Details	binding site for residue EDO C 603

Chain	Residue
C	ASP34
C	THR36
C	TYR38
C	HOH824
C	HOH825
C	HOH882

site_id	AC8
Number of Residues	5
Details	binding site for residue EDO C 604

Chain	Residue
C	ASP286
C	ALA289
C	ILE537
C	ILE539
C	HOH852

site_id	AC9
Number of Residues	5
Details	binding site for residue EDO C 605

Chain	Residue
C	PRO143
C	GLY189
C	PRO191
C	ARG478
C	HOH765

site_id	AD1
Number of Residues	6
Details	binding site for residue EDO C 606

Chain	Residue
C	TYR93
C	GLU423
C	GLN501
C	ARG513
C	ILE514
C	HOH897

site_id	AD2
Number of Residues	4
Details	binding site for residue EDO C 607

Chain	Residue
B	PRO70
B	THR73
C	GLN7
C	SER11

site_id	AD3
Number of Residues	3
Details	binding site for residue EDO C 608

Chain	Residue
C	LYS33
C	TYR35
C	HOH738

site_id	AD4
Number of Residues	6
Details	binding site for residue EDO C 609

Chain	Residue
C	HIS422
C	GLU423
C	GLY430
C	GLN501
C	HOH808
C	HOH1040

site_id	AD5
Number of Residues	12
Details	binding site for residue EDO C 610

Chain	Residue
B	PRO39
B	ARG76
B	GLU78
C	ALA334
C	ASP337
C	SER338
C	TYR544
C	HOH702
C	HOH705
C	HOH711
C	HOH766
C	HOH850

site_id	AD6
Number of Residues	4
Details	binding site for residue EDO C 611

Chain	Residue
B	ASP101
C	PRO229
C	ASP233
C	HOH1131

site_id	AD7
Number of Residues	2
Details	binding site for residue EDO C 612

Chain	Residue
C	HIS293
C	ASN295

site_id	AD8
Number of Residues	6
Details	binding site for residue EDO C 613

Chain	Residue
C	LYS185
C	LYS507
C	GLY509
C	HOH726
C	HOH1083
C	HOH1083

site_id	AD9
Number of Residues	9
Details	binding site for residue EDO C 614

Chain	Residue
C	PHE335
C	HOH716
C	HOH806
C	HOH929
B	HOH376
C	GLY46
C	LEU325
C	GLU331
C	ASP332

site_id	AE1
Number of Residues	11
Details	binding site for residue SO4 C 615

Chain	Residue
B	SER71
B	GLY72
B	THR73
C	SER11
C	TYR12
C	ASN43
C	LYS48
C	LYS326
C	ILE329
C	HOH1051
C	HOH1052

site_id	AE2
Number of Residues	4
Details	binding site for residue SO4 C 616

Chain	Residue
C	VAL558
C	LYS559
C	GLU560
C	HOH1070

site_id	AE3
Number of Residues	7
Details	binding site for residue SO4 C 617

Chain	Residue
C	SER204
C	ILE205
C	HOH730
C	HOH773
C	HOH865
C	HOH971
C	HOH1032

site_id	AE4
Number of Residues	13
Details	binding site for residue SO4 C 618

Chain	Residue
C	HIS222
C	GLU223
C	ASP224
C	HIS249
C	GLY280
C	LEU319
C	HIS323
C	ARG339
C	MET367
C	2PA619
C	HOH709
C	HOH729
C	HOH744

site_id	AE5
Number of Residues	16
Details	binding site for residue 2PA C 619

Chain	Residue
C	HIS137
C	HIS139
C	ALA170
C	KCX220
C	HIS222
C	HIS249
C	HIS275
C	GLY280
C	HIS323
C	ASP363
C	ALA366
C	MET367
C	NI601
C	NI602
C	SO4618
C	HOH729

site_id	AE6
Number of Residues	6
Details	binding site for residue SO4 C 620

Chain	Residue
C	LYS518
C	LYS518
C	HOH715
C	HOH715
C	HOH899
C	HOH899

Functional Information from PROSITE/UniProt

site_id	PS00145
Number of Residues	17
Details	UREASE_2 Urease active site. MVCHHLkqnIpeDVaFA

Chain	Residue	Details
C	MET320-ALA336

site_id	PS01120
Number of Residues	14
Details	UREASE_1 Urease nickel ligands signature. TAGGIDtHVHfinP

Chain	Residue	Details
C	THR130-PRO143

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000305

Chain	Residue	Details
C	HIS323

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01953, ECO:0000269\|PubMed:10368287, ECO:0000269\|PubMed:10766443, ECO:0000269\|PubMed:11713685, ECO:0000269\|PubMed:15038715, ECO:0000269\|PubMed:30969470, ECO:0000269\|DOI:10.1007/s007750050231

Chain	Residue	Details
C	HIS137
C	HIS275
C	ASP363

site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269\|PubMed:30969470

Chain	Residue	Details
C	HIS139
C	ALA170
C	HIS222
C	HIS249
C	ALA366

site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: via carbamate group => ECO:0000255\|HAMAP-Rule:MF_01953, ECO:0000269\|PubMed:10368287, ECO:0000269\|PubMed:10766443, ECO:0000269\|PubMed:11713685, ECO:0000269\|PubMed:15038715, ECO:0000269\|PubMed:30969470, ECO:0000269\|DOI:10.1007/s007750050231

Chain	Residue	Details
C	KCX220

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-carboxylysine => ECO:0000255\|HAMAP-Rule:MF_01953, ECO:0000269\|PubMed:10368287, ECO:0000269\|PubMed:10766443, ECO:0000269\|PubMed:11713685, ECO:0000269\|PubMed:15038715, ECO:0000269\|PubMed:30969470, ECO:0000269\|DOI:10.1007/s007750050231, ECO:0007744\|PDB:1IE7, ECO:0007744\|PDB:1S3T, ECO:0007744\|PDB:1UBP, ECO:0007744\|PDB:2UBP, ECO:0007744\|PDB:4UBP

Chain	Residue	Details
C	KCX220

226707

PDB entries from 2024-10-30

PDB statistics

PDBj update info

Contact PDBj

numon