6RMO

Structure of Plasmodium falciparum IMP-nucleotidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006190	biological_process	inosine salvage
A	0006204	biological_process	IMP catabolic process
A	0008253	molecular_function	5'-nucleotidase activity
A	0009117	biological_process	nucleotide metabolic process
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
A	0071590	biological_process	nicotinamide riboside biosynthetic process
A	0071592	biological_process	nicotinic acid riboside biosynthetic process
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006190	biological_process	inosine salvage
B	0006204	biological_process	IMP catabolic process
B	0008253	molecular_function	5'-nucleotidase activity
B	0009117	biological_process	nucleotide metabolic process
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
B	0071590	biological_process	nicotinamide riboside biosynthetic process
B	0071592	biological_process	nicotinic acid riboside biosynthetic process
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006190	biological_process	inosine salvage
C	0006204	biological_process	IMP catabolic process
C	0008253	molecular_function	5'-nucleotidase activity
C	0009117	biological_process	nucleotide metabolic process
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
C	0071590	biological_process	nicotinamide riboside biosynthetic process
C	0071592	biological_process	nicotinic acid riboside biosynthetic process
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006190	biological_process	inosine salvage
D	0006204	biological_process	IMP catabolic process
D	0008253	molecular_function	5'-nucleotidase activity
D	0009117	biological_process	nucleotide metabolic process
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
D	0071590	biological_process	nicotinamide riboside biosynthetic process
D	0071592	biological_process	nicotinic acid riboside biosynthetic process
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0003824	molecular_function	catalytic activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006190	biological_process	inosine salvage
E	0006204	biological_process	IMP catabolic process
E	0008253	molecular_function	5'-nucleotidase activity
E	0009117	biological_process	nucleotide metabolic process
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
E	0071590	biological_process	nicotinamide riboside biosynthetic process
E	0071592	biological_process	nicotinic acid riboside biosynthetic process
F	0000166	molecular_function	nucleotide binding
F	0000287	molecular_function	magnesium ion binding
F	0003824	molecular_function	catalytic activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006190	biological_process	inosine salvage
F	0006204	biological_process	IMP catabolic process
F	0008253	molecular_function	5'-nucleotidase activity
F	0009117	biological_process	nucleotide metabolic process
F	0016787	molecular_function	hydrolase activity
F	0046872	molecular_function	metal ion binding
F	0071590	biological_process	nicotinamide riboside biosynthetic process
F	0071592	biological_process	nicotinic acid riboside biosynthetic process
G	0000166	molecular_function	nucleotide binding
G	0000287	molecular_function	magnesium ion binding
G	0003824	molecular_function	catalytic activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006190	biological_process	inosine salvage
G	0006204	biological_process	IMP catabolic process
G	0008253	molecular_function	5'-nucleotidase activity
G	0009117	biological_process	nucleotide metabolic process
G	0016787	molecular_function	hydrolase activity
G	0046872	molecular_function	metal ion binding
G	0071590	biological_process	nicotinamide riboside biosynthetic process
G	0071592	biological_process	nicotinic acid riboside biosynthetic process
H	0000166	molecular_function	nucleotide binding
H	0000287	molecular_function	magnesium ion binding
H	0003824	molecular_function	catalytic activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006190	biological_process	inosine salvage
H	0006204	biological_process	IMP catabolic process
H	0008253	molecular_function	5'-nucleotidase activity
H	0009117	biological_process	nucleotide metabolic process
H	0016787	molecular_function	hydrolase activity
H	0046872	molecular_function	metal ion binding
H	0071590	biological_process	nicotinamide riboside biosynthetic process
H	0071592	biological_process	nicotinic acid riboside biosynthetic process
I	0000166	molecular_function	nucleotide binding
I	0000287	molecular_function	magnesium ion binding
I	0003824	molecular_function	catalytic activity
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0006190	biological_process	inosine salvage
I	0006204	biological_process	IMP catabolic process
I	0008253	molecular_function	5'-nucleotidase activity
I	0009117	biological_process	nucleotide metabolic process
I	0016787	molecular_function	hydrolase activity
I	0046872	molecular_function	metal ion binding
I	0071590	biological_process	nicotinamide riboside biosynthetic process
I	0071592	biological_process	nicotinic acid riboside biosynthetic process
J	0000166	molecular_function	nucleotide binding
J	0000287	molecular_function	magnesium ion binding
J	0003824	molecular_function	catalytic activity
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0006190	biological_process	inosine salvage
J	0006204	biological_process	IMP catabolic process
J	0008253	molecular_function	5'-nucleotidase activity
J	0009117	biological_process	nucleotide metabolic process
J	0016787	molecular_function	hydrolase activity
J	0046872	molecular_function	metal ion binding
J	0071590	biological_process	nicotinamide riboside biosynthetic process
J	0071592	biological_process	nicotinic acid riboside biosynthetic process
K	0000166	molecular_function	nucleotide binding
K	0000287	molecular_function	magnesium ion binding
K	0003824	molecular_function	catalytic activity
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0006190	biological_process	inosine salvage
K	0006204	biological_process	IMP catabolic process
K	0008253	molecular_function	5'-nucleotidase activity
K	0009117	biological_process	nucleotide metabolic process
K	0016787	molecular_function	hydrolase activity
K	0046872	molecular_function	metal ion binding
K	0071590	biological_process	nicotinamide riboside biosynthetic process
K	0071592	biological_process	nicotinic acid riboside biosynthetic process
L	0000166	molecular_function	nucleotide binding
L	0000287	molecular_function	magnesium ion binding
L	0003824	molecular_function	catalytic activity
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0006190	biological_process	inosine salvage
L	0006204	biological_process	IMP catabolic process
L	0008253	molecular_function	5'-nucleotidase activity
L	0009117	biological_process	nucleotide metabolic process
L	0016787	molecular_function	hydrolase activity
L	0046872	molecular_function	metal ion binding
L	0071590	biological_process	nicotinamide riboside biosynthetic process
L	0071592	biological_process	nicotinic acid riboside biosynthetic process
M	0000166	molecular_function	nucleotide binding
M	0000287	molecular_function	magnesium ion binding
M	0003824	molecular_function	catalytic activity
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0006190	biological_process	inosine salvage
M	0006204	biological_process	IMP catabolic process
M	0008253	molecular_function	5'-nucleotidase activity
M	0009117	biological_process	nucleotide metabolic process
M	0016787	molecular_function	hydrolase activity
M	0046872	molecular_function	metal ion binding
M	0071590	biological_process	nicotinamide riboside biosynthetic process
M	0071592	biological_process	nicotinic acid riboside biosynthetic process
N	0000166	molecular_function	nucleotide binding
N	0000287	molecular_function	magnesium ion binding
N	0003824	molecular_function	catalytic activity
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0006190	biological_process	inosine salvage
N	0006204	biological_process	IMP catabolic process
N	0008253	molecular_function	5'-nucleotidase activity
N	0009117	biological_process	nucleotide metabolic process
N	0016787	molecular_function	hydrolase activity
N	0046872	molecular_function	metal ion binding
N	0071590	biological_process	nicotinamide riboside biosynthetic process
N	0071592	biological_process	nicotinic acid riboside biosynthetic process
O	0000166	molecular_function	nucleotide binding
O	0000287	molecular_function	magnesium ion binding
O	0003824	molecular_function	catalytic activity
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0006190	biological_process	inosine salvage
O	0006204	biological_process	IMP catabolic process
O	0008253	molecular_function	5'-nucleotidase activity
O	0009117	biological_process	nucleotide metabolic process
O	0016787	molecular_function	hydrolase activity
O	0046872	molecular_function	metal ion binding
O	0071590	biological_process	nicotinamide riboside biosynthetic process
O	0071592	biological_process	nicotinic acid riboside biosynthetic process
P	0000166	molecular_function	nucleotide binding
P	0000287	molecular_function	magnesium ion binding
P	0003824	molecular_function	catalytic activity
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0006190	biological_process	inosine salvage
P	0006204	biological_process	IMP catabolic process
P	0008253	molecular_function	5'-nucleotidase activity
P	0009117	biological_process	nucleotide metabolic process
P	0016787	molecular_function	hydrolase activity
P	0046872	molecular_function	metal ion binding
P	0071590	biological_process	nicotinamide riboside biosynthetic process
P	0071592	biological_process	nicotinic acid riboside biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"32591529","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"32591529","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32591529","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RMD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	137
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32591529","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RME","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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