6RG0
Structure of pdxj
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008615 | biological_process | pyridoxine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| A | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008615 | biological_process | pyridoxine biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| B | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| B | 0042802 | molecular_function | identical protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008615 | biological_process | pyridoxine biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| C | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| C | 0042802 | molecular_function | identical protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008615 | biological_process | pyridoxine biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| D | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| D | 0042802 | molecular_function | identical protein binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | HIS58 | |
| A | GLU85 | |
| B | HIS58 | |
| B | GLU85 | |
| C | HIS58 | |
| C | GLU85 | |
| D | HIS58 | |
| D | GLU85 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| A | HIS206 | |
| B | HIS206 | |
| C | HIS206 | |
| D | HIS206 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | ASN22 | |
| B | ASP24 | |
| B | ARG33 | |
| B | ARG60 | |
| B | HIS65 | |
| B | THR115 | |
| B | GLY207 | |
| B | GLY228 | |
| C | ASN22 | |
| C | ASP24 | |
| C | ARG33 | |
| C | ARG60 | |
| C | HIS65 | |
| C | THR115 | |
| C | GLY207 | |
| C | GLY228 | |
| D | ASN22 | |
| D | ASP24 | |
| D | ARG33 | |
| D | ARG60 | |
| D | HIS65 | |
| D | THR115 | |
| D | GLY207 | |
| D | GLY228 | |
| A | THR115 | |
| A | GLY207 | |
| A | GLY228 | |
| A | ASN22 | |
| A | ASP24 | |
| A | ARG33 | |
| A | ARG60 | |
| A | HIS65 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Transition state stabilizer |
| Chain | Residue | Details |
| A | GLU166 | |
| B | GLU166 | |
| C | GLU166 | |
| D | GLU166 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 9 |
| Details | M-CSA 243 |
| Chain | Residue | Details |
| A | ASN22 | electrostatic stabiliser, hydrogen bond donor |
| A | HIS25 | attractive charge-charge interaction, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | HIS58 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ARG60 | attractive charge-charge interaction, electrostatic stabiliser, increase acidity, increase basicity |
| A | ARG64 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond donor, increase acidity, increase basicity |
| A | GLU85 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| A | THR116 | electrostatic stabiliser, hydrogen bond acceptor |
| A | GLU166 | electrostatic stabiliser, hydrogen bond acceptor |
| A | HIS206 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 9 |
| Details | M-CSA 243 |
| Chain | Residue | Details |
| B | ASN22 | electrostatic stabiliser, hydrogen bond donor |
| B | HIS25 | attractive charge-charge interaction, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | HIS58 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | ARG60 | attractive charge-charge interaction, electrostatic stabiliser, increase acidity, increase basicity |
| B | ARG64 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond donor, increase acidity, increase basicity |
| B | GLU85 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| B | THR116 | electrostatic stabiliser, hydrogen bond acceptor |
| B | GLU166 | electrostatic stabiliser, hydrogen bond acceptor |
| B | HIS206 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 9 |
| Details | M-CSA 243 |
| Chain | Residue | Details |
| C | ASN22 | electrostatic stabiliser, hydrogen bond donor |
| C | HIS25 | attractive charge-charge interaction, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | HIS58 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | ARG60 | attractive charge-charge interaction, electrostatic stabiliser, increase acidity, increase basicity |
| C | ARG64 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond donor, increase acidity, increase basicity |
| C | GLU85 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| C | THR116 | electrostatic stabiliser, hydrogen bond acceptor |
| C | GLU166 | electrostatic stabiliser, hydrogen bond acceptor |
| C | HIS206 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA4 |
| Number of Residues | 9 |
| Details | M-CSA 243 |
| Chain | Residue | Details |
| D | HIS206 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | ASN22 | electrostatic stabiliser, hydrogen bond donor |
| D | HIS25 | attractive charge-charge interaction, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | HIS58 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | ARG60 | attractive charge-charge interaction, electrostatic stabiliser, increase acidity, increase basicity |
| D | ARG64 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond donor, increase acidity, increase basicity |
| D | GLU85 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| D | THR116 | electrostatic stabiliser, hydrogen bond acceptor |
| D | GLU166 | electrostatic stabiliser, hydrogen bond acceptor |
