Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | HIS673 |
| A | HIS709 |
| A | ASP710 |
| A | ASP822 |
| A | HOH1113 |
| A | HOH1128 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | HOH1181 |
| A | HOH1193 |
| A | HOH1201 |
| A | ASP710 |
| A | HOH1113 |
| A | HOH1120 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 1003 |
| Chain | Residue |
| A | GLU765 |
| A | ALA767 |
| A | GLU768 |
| A | HOH1168 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue GAI A 1004 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 1005 |
| Chain | Residue |
| A | GLY688 |
| A | ASN689 |
| A | GLU692 |
| A | LYS693 |
| A | LEU894 |
| A | GLN895 |
| A | GLY896 |
| A | HOH1135 |
| A | HOH1170 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GAI A 1006 |
| Chain | Residue |
| A | LEU753 |
| A | SER754 |
| A | ASP759 |
| A | ASP762 |
| A | LEU915 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue K1Q A 1007 |
| Chain | Residue |
| A | MET785 |
| A | ASP822 |
| A | ASN825 |
| A | MET861 |
| A | GLY873 |
| A | GLN874 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GAI B 1001 |
| Chain | Residue |
| A | GLU696 |
| B | TYR686 |
| B | ASN689 |
| B | TYR691 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 1002 |
| Chain | Residue |
| B | HIS673 |
| B | HIS709 |
| B | ASP710 |
| B | ASP822 |
| B | HOH1119 |
| B | HOH1122 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1003 |
| Chain | Residue |
| B | ASP710 |
| B | HOH1102 |
| B | HOH1122 |
| B | HOH1130 |
| B | HOH1154 |
| B | HOH1200 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue GAI B 1004 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 1005 |
| Chain | Residue |
| A | TYR691 |
| A | LEU694 |
| B | TYR691 |
| B | LEU694 |
| B | HOH1162 |
| B | HOH1172 |
| B | HOH1173 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 1006 |
| Chain | Residue |
| B | GLY688 |
| B | ASN689 |
| B | GLU692 |
| B | LYS693 |
| B | LEU894 |
| B | GLY896 |
| B | HOH1156 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for residue K1Q B 1007 |
| Chain | Residue |
| B | MET785 |
| B | ASP822 |
| B | ILE823 |
| B | ASN825 |
| B | VAL840 |
| B | MET861 |
| B | GLY873 |
| B | GLN874 |
| B | PHE877 |
| B | PHE880 |
| B | HOH1194 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHmGlnNsF |
| Chain | Residue | Details |
| A | HIS709-PHE720 | |
