6RFT
Crystal structure of Eis2 from Mycobacterium abscessus bound to Acetyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| A | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| B | 0008080 | molecular_function | N-acetyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| B | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| C | 0008080 | molecular_function | N-acetyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| C | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| D | 0008080 | molecular_function | N-acetyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| D | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| E | 0008080 | molecular_function | N-acetyltransferase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016746 | molecular_function | acyltransferase activity |
| E | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| E | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| F | 0008080 | molecular_function | N-acetyltransferase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016746 | molecular_function | acyltransferase activity |
| F | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| F | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue ACO A 501 |
| Chain | Residue |
| A | VAL25 |
| A | LEU94 |
| A | LEU95 |
| A | THR96 |
| A | PHE117 |
| A | SER119 |
| A | GLU120 |
| A | ILE123 |
| A | TYR124 |
| A | ARG126 |
| A | HOH608 |
| A | PHE26 |
| A | HOH623 |
| F | ASP266 |
| F | LEU267 |
| A | ALA82 |
| A | VAL83 |
| A | VAL85 |
| A | ARG90 |
| A | ARG91 |
| A | ARG92 |
| A | GLY93 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue ACO B 501 |
| Chain | Residue |
| B | VAL25 |
| B | PHE26 |
| B | ALA82 |
| B | VAL83 |
| B | VAL85 |
| B | ARG90 |
| B | ARG91 |
| B | ARG92 |
| B | GLY93 |
| B | LEU94 |
| B | LEU95 |
| B | THR96 |
| B | PHE117 |
| B | SER119 |
| B | GLU120 |
| B | LEU122 |
| B | ILE123 |
| B | TYR124 |
| B | ARG126 |
| B | HOH605 |
| B | HOH614 |
| B | HOH697 |
| E | ASP266 |
| E | LEU267 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue ACO C 501 |
| Chain | Residue |
| B | ASP266 |
| B | LEU267 |
| C | VAL25 |
| C | PHE26 |
| C | VAL83 |
| C | VAL85 |
| C | ARG90 |
| C | ARG91 |
| C | ARG92 |
| C | GLY93 |
| C | LEU95 |
| C | THR96 |
| C | LEU116 |
| C | PHE117 |
| C | SER119 |
| C | GLU120 |
| C | ILE123 |
| C | TYR124 |
| C | ARG126 |
| C | HOH605 |
| C | HOH615 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue ACO D 501 |
| Chain | Residue |
| A | ASP266 |
| D | VAL25 |
| D | VAL83 |
| D | VAL85 |
| D | ARG90 |
| D | ARG91 |
| D | ARG92 |
| D | GLY93 |
| D | LEU95 |
| D | THR96 |
| D | GLU120 |
| D | LEU122 |
| D | ILE123 |
| D | ARG126 |
| D | HOH616 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | binding site for residue ACO E 501 |
| Chain | Residue |
| C | ASP266 |
| E | VAL25 |
| E | VAL83 |
| E | VAL85 |
| E | ARG90 |
| E | ARG91 |
| E | ARG92 |
| E | GLY93 |
| E | LEU95 |
| E | THR96 |
| E | GLU120 |
| E | LEU122 |
| E | ILE123 |
| E | ARG126 |
| E | HOH621 |
| E | HOH622 |
| E | HOH668 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | binding site for residue ACO F 501 |
| Chain | Residue |
| D | ASP266 |
| F | VAL25 |
| F | PHE26 |
| F | VAL83 |
| F | VAL85 |
| F | ARG90 |
| F | ARG91 |
| F | ARG92 |
| F | GLY93 |
| F | LEU94 |
| F | LEU95 |
| F | THR96 |
| F | ILE123 |
| F | TYR124 |
| F | ARG126 |
| F | HOH608 |
| F | HOH609 |
