6RD4

CryoEM structure of Polytomella F-ATP synthase, Full dimer, composite map

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0006811	biological_process	monoatomic ion transport
A	0008289	molecular_function	lipid binding
A	0015078	molecular_function	proton transmembrane transporter activity
A	0015986	biological_process	proton motive force-driven ATP synthesis
A	0016020	cellular_component	membrane
A	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	1902600	biological_process	proton transmembrane transport
B	0005739	cellular_component	mitochondrion
B	0006811	biological_process	monoatomic ion transport
B	0008289	molecular_function	lipid binding
B	0015078	molecular_function	proton transmembrane transporter activity
B	0015986	biological_process	proton motive force-driven ATP synthesis
B	0016020	cellular_component	membrane
B	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	1902600	biological_process	proton transmembrane transport
C	0005739	cellular_component	mitochondrion
C	0006811	biological_process	monoatomic ion transport
C	0008289	molecular_function	lipid binding
C	0015078	molecular_function	proton transmembrane transporter activity
C	0015986	biological_process	proton motive force-driven ATP synthesis
C	0016020	cellular_component	membrane
C	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	1902600	biological_process	proton transmembrane transport
D	0005739	cellular_component	mitochondrion
D	0006811	biological_process	monoatomic ion transport
D	0008289	molecular_function	lipid binding
D	0015078	molecular_function	proton transmembrane transporter activity
D	0015986	biological_process	proton motive force-driven ATP synthesis
D	0016020	cellular_component	membrane
D	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
D	0045259	cellular_component	proton-transporting ATP synthase complex
D	1902600	biological_process	proton transmembrane transport
E	0005739	cellular_component	mitochondrion
E	0006811	biological_process	monoatomic ion transport
E	0008289	molecular_function	lipid binding
E	0015078	molecular_function	proton transmembrane transporter activity
E	0015986	biological_process	proton motive force-driven ATP synthesis
E	0016020	cellular_component	membrane
E	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
E	0045259	cellular_component	proton-transporting ATP synthase complex
E	1902600	biological_process	proton transmembrane transport
F	0005739	cellular_component	mitochondrion
F	0006811	biological_process	monoatomic ion transport
F	0008289	molecular_function	lipid binding
F	0015078	molecular_function	proton transmembrane transporter activity
F	0015986	biological_process	proton motive force-driven ATP synthesis
F	0016020	cellular_component	membrane
F	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
F	0045259	cellular_component	proton-transporting ATP synthase complex
F	1902600	biological_process	proton transmembrane transport
G	0005739	cellular_component	mitochondrion
G	0006811	biological_process	monoatomic ion transport
G	0008289	molecular_function	lipid binding
G	0015078	molecular_function	proton transmembrane transporter activity
G	0015986	biological_process	proton motive force-driven ATP synthesis
G	0016020	cellular_component	membrane
G	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
G	0045259	cellular_component	proton-transporting ATP synthase complex
G	1902600	biological_process	proton transmembrane transport
H	0005739	cellular_component	mitochondrion
H	0006811	biological_process	monoatomic ion transport
H	0008289	molecular_function	lipid binding
H	0015078	molecular_function	proton transmembrane transporter activity
H	0015986	biological_process	proton motive force-driven ATP synthesis
H	0016020	cellular_component	membrane
H	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
H	0045259	cellular_component	proton-transporting ATP synthase complex
H	1902600	biological_process	proton transmembrane transport
I	0005739	cellular_component	mitochondrion
I	0006811	biological_process	monoatomic ion transport
I	0008289	molecular_function	lipid binding
I	0015078	molecular_function	proton transmembrane transporter activity
I	0015986	biological_process	proton motive force-driven ATP synthesis
I	0016020	cellular_component	membrane
I	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
I	0045259	cellular_component	proton-transporting ATP synthase complex
I	1902600	biological_process	proton transmembrane transport
J	0005739	cellular_component	mitochondrion
J	0006811	biological_process	monoatomic ion transport
J	0008289	molecular_function	lipid binding
J	0015078	molecular_function	proton transmembrane transporter activity
J	0015986	biological_process	proton motive force-driven ATP synthesis
J	0016020	cellular_component	membrane
J	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
J	0045259	cellular_component	proton-transporting ATP synthase complex
J	1902600	biological_process	proton transmembrane transport
M	0006754	biological_process	ATP biosynthetic process
M	0006811	biological_process	monoatomic ion transport
M	0015078	molecular_function	proton transmembrane transporter activity
M	0015986	biological_process	proton motive force-driven ATP synthesis
M	0016020	cellular_component	membrane
M	0045259	cellular_component	proton-transporting ATP synthase complex
M	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
M	1902600	biological_process	proton transmembrane transport
P	0006754	biological_process	ATP biosynthetic process
P	0006811	biological_process	monoatomic ion transport
P	0015986	biological_process	proton motive force-driven ATP synthesis
P	0016020	cellular_component	membrane
P	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
P	1902600	biological_process	proton transmembrane transport
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0015986	biological_process	proton motive force-driven ATP synthesis
Q	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
Q	0045259	cellular_component	proton-transporting ATP synthase complex
Q	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0006811	biological_process	monoatomic ion transport
R	0015986	biological_process	proton motive force-driven ATP synthesis
R	0016020	cellular_component	membrane
R	0045259	cellular_component	proton-transporting ATP synthase complex
R	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
R	1902600	biological_process	proton transmembrane transport
S	0015986	biological_process	proton motive force-driven ATP synthesis
S	0045259	cellular_component	proton-transporting ATP synthase complex
S	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
T	0000166	molecular_function	nucleotide binding
T	0005524	molecular_function	ATP binding
T	0005743	cellular_component	mitochondrial inner membrane
T	0006754	biological_process	ATP biosynthetic process
T	0006811	biological_process	monoatomic ion transport
T	0015986	biological_process	proton motive force-driven ATP synthesis
T	0016787	molecular_function	hydrolase activity
T	0032559	molecular_function	adenyl ribonucleotide binding
T	0043531	molecular_function	ADP binding
T	0045259	cellular_component	proton-transporting ATP synthase complex
T	0046034	biological_process	ATP metabolic process
T	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
T	1902600	biological_process	proton transmembrane transport
U	0000166	molecular_function	nucleotide binding
U	0005524	molecular_function	ATP binding
U	0005743	cellular_component	mitochondrial inner membrane
U	0006754	biological_process	ATP biosynthetic process
U	0006811	biological_process	monoatomic ion transport
U	0015986	biological_process	proton motive force-driven ATP synthesis
U	0016787	molecular_function	hydrolase activity
U	0032559	molecular_function	adenyl ribonucleotide binding
U	0043531	molecular_function	ADP binding
U	0045259	cellular_component	proton-transporting ATP synthase complex
U	0046034	biological_process	ATP metabolic process
U	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
U	1902600	biological_process	proton transmembrane transport
V	0000166	molecular_function	nucleotide binding
V	0005524	molecular_function	ATP binding
V	0005743	cellular_component	mitochondrial inner membrane
V	0006754	biological_process	ATP biosynthetic process
V	0006811	biological_process	monoatomic ion transport
V	0015986	biological_process	proton motive force-driven ATP synthesis
V	0016787	molecular_function	hydrolase activity
V	0032559	molecular_function	adenyl ribonucleotide binding
V	0043531	molecular_function	ADP binding
V	0045259	cellular_component	proton-transporting ATP synthase complex
V	0046034	biological_process	ATP metabolic process
V	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
V	1902600	biological_process	proton transmembrane transport
X	0000166	molecular_function	nucleotide binding
X	0005524	molecular_function	ATP binding
X	0005743	cellular_component	mitochondrial inner membrane
X	0006754	biological_process	ATP biosynthetic process
X	0006811	biological_process	monoatomic ion transport
X	0015986	biological_process	proton motive force-driven ATP synthesis
X	0016787	molecular_function	hydrolase activity
X	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
X	0045259	cellular_component	proton-transporting ATP synthase complex
X	0046034	biological_process	ATP metabolic process
X	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
X	1902600	biological_process	proton transmembrane transport
Y	0000166	molecular_function	nucleotide binding
Y	0005524	molecular_function	ATP binding
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0006754	biological_process	ATP biosynthetic process
Y	0006811	biological_process	monoatomic ion transport
Y	0015986	biological_process	proton motive force-driven ATP synthesis
Y	0016787	molecular_function	hydrolase activity
Y	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
Y	0045259	cellular_component	proton-transporting ATP synthase complex
Y	0046034	biological_process	ATP metabolic process
Y	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
Y	1902600	biological_process	proton transmembrane transport
Z	0000166	molecular_function	nucleotide binding
Z	0005524	molecular_function	ATP binding
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0006754	biological_process	ATP biosynthetic process
Z	0006811	biological_process	monoatomic ion transport
Z	0015986	biological_process	proton motive force-driven ATP synthesis
Z	0016787	molecular_function	hydrolase activity
Z	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
Z	0045259	cellular_component	proton-transporting ATP synthase complex
Z	0046034	biological_process	ATP metabolic process
Z	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
Z	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN M 600

Chain	Residue
6	HOH204
M	HIS248
M	HIS252
M	HOH706

---

site_id	AC2
Number of Residues	15
Details	binding site for residue ATP T 1001

Chain	Residue
T	THR232
T	ALA233
T	GLU384
T	PHE413
T	ARG418
T	PRO419
T	GLN486
T	GLN488
T	MG1002
X	ARG385
T	ARG227
T	GLN228
T	THR229
T	GLY230
T	LYS231

---

site_id	AC3
Number of Residues	3
Details	binding site for residue MG T 1002

Chain	Residue
T	THR232
T	ASP325
T	ATP1001

---

site_id	AC4
Number of Residues	14
Details	binding site for residue ATP U 1001

Chain	Residue
U	GLN228
U	THR229
U	GLY230
U	LYS231
U	THR232
U	ALA233
U	GLU384
U	PHE413
U	ARG418
U	GLN486
U	GLN488
U	MG1002
Z	ARG385
Z	ASN388

---

site_id	AC5
Number of Residues	2
Details	binding site for residue MG U 1002

Chain	Residue
U	THR232
U	ATP1001

---

site_id	AC6
Number of Residues	14
Details	binding site for residue ATP V 1000

Chain	Residue
V	ARG227
V	GLN228
V	THR229
V	GLY230
V	LYS231
V	THR232
V	ALA233
V	PHE413
V	ARG418
V	GLN486
V	GLN488
V	MG1001
Y	ARG385
Y	ASN388

---

site_id	AC7
Number of Residues	3
Details	binding site for residue MG V 1001

Chain	Residue
V	THR232
V	ASP325
V	ATP1000

---

site_id	AC8
Number of Residues	12
Details	binding site for residue ADP X 601

Chain	Residue
U	VAL427
U	ARG429
X	ALA185
X	GLY186
X	GLY188
X	LYS189
X	THR190
X	VAL191
X	TYR374
X	PHE447
X	PHE453
X	MG602

---

site_id	AC9
Number of Residues	4
Details	binding site for residue MG X 602

Chain	Residue
X	THR190
X	GLU215
X	ARG216
X	ADP601

---

site_id	AD1
Number of Residues	13
Details	binding site for residue ADP Y 601

Chain	Residue
T	ARG429
Y	GLY184
Y	GLY186
Y	GLY188
Y	LYS189
Y	THR190
Y	VAL191
Y	TYR374
Y	PHE447
Y	ALA450
Y	PHE453
Y	THR454
Y	MG602

---

site_id	AD2
Number of Residues	5
Details	binding site for residue MG Y 602

Chain	Residue
Y	THR190
Y	GLU215
Y	GLU219
Y	ASP285
Y	ADP601

---

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PALNVGLSVS

Chain	Residue	Details
U	PRO419-SER428
X	PRO375-SER384

---

site_id	PS00153
Number of Residues	14
Details	ATPASE_GAMMA ATP synthase gamma subunit signature. ITtEliEiiaGAsA

Chain	Residue	Details
S	ILE300-ALA313

---

site_id	PS00389
Number of Residues	20
Details	ATPASE_DELTA ATP synthase delta (OSCP) subunit signature. LvMqekIDkKLlGGFVIEfS

Chain	Residue	Details
P	LEU184-SER203

---

site_id	PS00449
Number of Residues	10
Details	ATPASE_A ATP synthase a subunit signature. SLGVRLWVNM

Chain	Residue	Details
M	SER235-MET244

---

site_id	PS00605
Number of Residues	22
Details	ATPASE_C ATP synthase c subunit signature. ARNPniakqLvGyaLLgfaLtE

Chain	Residue	Details
A	ALA90-GLU111

---