6R7Z

CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005227	molecular_function	calcium-activated cation channel activity
A	0005229	molecular_function	intracellularly calcium-gated chloride channel activity
A	0005254	molecular_function	chloride channel activity
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0098655	biological_process	monoatomic cation transmembrane transport
A	1902476	biological_process	chloride transmembrane transport
B	0005227	molecular_function	calcium-activated cation channel activity
B	0005229	molecular_function	intracellularly calcium-gated chloride channel activity
B	0005254	molecular_function	chloride channel activity
B	0005886	cellular_component	plasma membrane
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0098655	biological_process	monoatomic cation transmembrane transport
B	1902476	biological_process	chloride transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	320
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	80
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	222
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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