Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0000307 | cellular_component | cyclin-dependent protein kinase holoenzyme complex |
B | 0005515 | molecular_function | protein binding |
B | 0005634 | cellular_component | nucleus |
B | 0005654 | cellular_component | nucleoplasm |
B | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
B | 0016538 | molecular_function | cyclin-dependent protein serine/threonine kinase regulator activity |
B | 0016592 | cellular_component | mediator complex |
B | 0042802 | molecular_function | identical protein binding |
B | 0045023 | biological_process | G0 to G1 transition |
B | 0045746 | biological_process | negative regulation of Notch signaling pathway |
B | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
B | 1990508 | cellular_component | CKM complex |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue JRE A 501 |
Chain | Residue |
A | VAL27 |
A | LEU158 |
A | ALA172 |
A | ASP173 |
A | ARG356 |
A | HOH623 |
A | HOH684 |
A | GLY28 |
A | ALA50 |
A | ILE79 |
A | PHE97 |
A | ASP98 |
A | ALA100 |
A | ASP103 |
A | ALA155 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue EDO B 301 |
Chain | Residue |
A | ARG71 |
A | LYS83 |
A | VAL84 |
B | ASP147 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue FMT B 302 |
Chain | Residue |
B | ALA0 |
B | VAL152 |
B | TYR153 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue FMT B 303 |
Chain | Residue |
B | GLN41 |
B | PHE69 |
B | HOH402 |
B | HOH410 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue FMT B 304 |
Chain | Residue |
B | LYS27 |
B | TYR76 |
B | SER77 |
B | SER80 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 26 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGRGTYGHVYkAkrkdgkddkd........YALK |
Chain | Residue | Details |
A | VAL27-LYS52 | |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpaNILV |
Chain | Residue | Details |
A | VAL147-VAL159 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
B | SER275 | |
Chain | Residue | Details |
A | VAL27 | |
A | LYS52 | |