6R3P

Crystal structure of human DMC1 ATPase domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000150	molecular_function	DNA strand exchange activity
A	0003677	molecular_function	DNA binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0006259	biological_process	DNA metabolic process
A	0006281	biological_process	DNA repair
A	0007131	biological_process	reciprocal meiotic recombination
A	0008094	molecular_function	ATP-dependent activity, acting on DNA
A	0140664	molecular_function	ATP-dependent DNA damage sensor activity
B	0000150	molecular_function	DNA strand exchange activity
B	0003677	molecular_function	DNA binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0006259	biological_process	DNA metabolic process
B	0006281	biological_process	DNA repair
B	0007131	biological_process	reciprocal meiotic recombination
B	0008094	molecular_function	ATP-dependent activity, acting on DNA
B	0140664	molecular_function	ATP-dependent DNA damage sensor activity
C	0000150	molecular_function	DNA strand exchange activity
C	0003677	molecular_function	DNA binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0006259	biological_process	DNA metabolic process
C	0006281	biological_process	DNA repair
C	0007131	biological_process	reciprocal meiotic recombination
C	0008094	molecular_function	ATP-dependent activity, acting on DNA
C	0140664	molecular_function	ATP-dependent DNA damage sensor activity
D	0000150	molecular_function	DNA strand exchange activity
D	0003677	molecular_function	DNA binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0006259	biological_process	DNA metabolic process
D	0006281	biological_process	DNA repair
D	0007131	biological_process	reciprocal meiotic recombination
D	0008094	molecular_function	ATP-dependent activity, acting on DNA
D	0140664	molecular_function	ATP-dependent DNA damage sensor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue EDO A 401

Chain	Residue
A	LYS255
B	HIS198

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site_id	AC2
Number of Residues	4
Details	binding site for residue EDO A 402

Chain	Residue
A	TYR91
A	LYS94
A	HOH528
B	ARG192

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site_id	AC3
Number of Residues	3
Details	binding site for residue PEG C 401

Chain	Residue
C	ALA207
C	TYR260
C	P6G403

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site_id	AC4
Number of Residues	4
Details	binding site for residue PG4 C 402

Chain	Residue
C	SER251
C	ARG252
C	LYS255
D	HIS198

---

site_id	AC5
Number of Residues	4
Details	binding site for residue P6G C 403

Chain	Residue
C	TYR205
C	TYR260
C	TYR260
C	PEG401

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site_id	AC6
Number of Residues	6
Details	binding site for residue P6G D 401

Chain	Residue
D	TYR205
D	ALA208
D	TYR260
D	TYR260
D	PEG402
D	1PE403

---

site_id	AC7
Number of Residues	4
Details	binding site for residue PEG D 402

Chain	Residue
D	LYS255
D	TYR260
D	P6G401
D	1PE403

---

site_id	AC8
Number of Residues	5
Details	binding site for residue 1PE D 403

Chain	Residue
C	HIS198
D	ARG252
D	LYS255
D	P6G401
D	PEG402

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15125839","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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