6R3P
Crystal structure of human DMC1 ATPase domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000150 | molecular_function | DNA strand exchange activity |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006281 | biological_process | DNA repair |
| A | 0007131 | biological_process | reciprocal meiotic recombination |
| A | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| A | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| B | 0000150 | molecular_function | DNA strand exchange activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0006259 | biological_process | DNA metabolic process |
| B | 0006281 | biological_process | DNA repair |
| B | 0007131 | biological_process | reciprocal meiotic recombination |
| B | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| B | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| C | 0000150 | molecular_function | DNA strand exchange activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0006259 | biological_process | DNA metabolic process |
| C | 0006281 | biological_process | DNA repair |
| C | 0007131 | biological_process | reciprocal meiotic recombination |
| C | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| C | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| D | 0000150 | molecular_function | DNA strand exchange activity |
| D | 0003677 | molecular_function | DNA binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0006259 | biological_process | DNA metabolic process |
| D | 0006281 | biological_process | DNA repair |
| D | 0007131 | biological_process | reciprocal meiotic recombination |
| D | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| D | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | LYS255 |
| B | HIS198 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | TYR91 |
| A | LYS94 |
| A | HOH528 |
| B | ARG192 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue PEG C 401 |
| Chain | Residue |
| C | ALA207 |
| C | TYR260 |
| C | P6G403 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue PG4 C 402 |
| Chain | Residue |
| C | SER251 |
| C | ARG252 |
| C | LYS255 |
| D | HIS198 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue P6G C 403 |
| Chain | Residue |
| C | TYR205 |
| C | TYR260 |
| C | TYR260 |
| C | PEG401 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue P6G D 401 |
| Chain | Residue |
| D | TYR205 |
| D | ALA208 |
| D | TYR260 |
| D | TYR260 |
| D | PEG402 |
| D | 1PE403 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue PEG D 402 |
| Chain | Residue |
| D | LYS255 |
| D | TYR260 |
| D | P6G401 |
| D | 1PE403 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE D 403 |
| Chain | Residue |
| C | HIS198 |
| D | ARG252 |
| D | LYS255 |
| D | P6G401 |
| D | PEG402 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | GLY126 | |
| B | GLY126 | |
| C | GLY126 | |
| D | GLY126 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15125839 |
| Chain | Residue | Details |
| A | ARG230 | |
| B | ARG311 | |
| C | ARG230 | |
| C | PHE233 | |
| C | ARG236 | |
| C | ARG242 | |
| C | ARG311 | |
| D | ARG230 | |
| D | PHE233 | |
| D | ARG236 | |
| D | ARG242 | |
| A | PHE233 | |
| D | ARG311 | |
| A | ARG236 | |
| A | ARG242 | |
| A | ARG311 | |
| B | ARG230 | |
| B | PHE233 | |
| B | ARG236 | |
| B | ARG242 |
