Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0015267 | molecular_function | channel activity |
A | 0016020 | cellular_component | membrane |
A | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue GOL A 301 |
Chain | Residue |
A | GLY86 |
A | GLY90 |
A | ASN195 |
A | GLU202 |
A | HOH402 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue GOL A 302 |
Chain | Residue |
A | ARG229 |
A | GOL308 |
A | GOL312 |
A | HOH405 |
A | PHE74 |
A | GLY222 |
A | TYR223 |
A | ALA224 |
site_id | AC3 |
Number of Residues | 6 |
Details | binding site for residue GOL A 303 |
Chain | Residue |
A | LEU60 |
A | ASN61 |
A | ALA137 |
A | HIS140 |
A | HIS165 |
A | MET219 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue GOL A 304 |
Chain | Residue |
A | ALA103 |
A | TRP109 |
A | THR149 |
A | HOH406 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue GOL A 305 |
Chain | Residue |
A | ARG35 |
A | GLU193 |
A | ILE276 |
A | THR279 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue GOL A 306 |
Chain | Residue |
A | GLY156 |
A | ALA159 |
A | THR160 |
A | TYR161 |
A | GOL308 |
A | HOH425 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue GOL A 307 |
Chain | Residue |
A | MET58 |
A | VAL59 |
A | ASN61 |
A | LYS62 |
A | PHE141 |
A | HOH417 |
site_id | AC8 |
Number of Residues | 7 |
Details | binding site for residue GOL A 308 |
Chain | Residue |
A | VAL55 |
A | VAL70 |
A | GLY222 |
A | ARG229 |
A | GOL302 |
A | GOL306 |
A | HOH403 |
site_id | AC9 |
Number of Residues | 7 |
Details | binding site for residue GOL A 309 |
Chain | Residue |
A | LYS62 |
A | GLY65 |
A | SER66 |
A | SER66 |
A | TYR67 |
A | LEU68 |
A | HOH416 |
site_id | AD1 |
Number of Residues | 3 |
Details | binding site for residue GOL A 310 |
Chain | Residue |
A | SER132 |
A | TYR135 |
A | ARG170 |
site_id | AD2 |
Number of Residues | 3 |
Details | binding site for residue GOL A 311 |
Chain | Residue |
A | ARG106 |
A | THR190 |
A | ASP191 |
site_id | AD3 |
Number of Residues | 9 |
Details | binding site for residue GOL A 312 |
Chain | Residue |
A | VAL78 |
A | HIS92 |
A | ASN94 |
A | ASN226 |
A | GOL302 |
A | GOL313 |
A | HOH401 |
A | HOH404 |
A | HOH405 |
site_id | AD4 |
Number of Residues | 10 |
Details | binding site for residue GOL A 313 |
Chain | Residue |
A | ALA91 |
A | HIS92 |
A | MET93 |
A | ASN94 |
A | LEU182 |
A | LEU186 |
A | GOL312 |
A | HOH401 |
A | HOH404 |
A | HOH434 |
site_id | AD5 |
Number of Residues | 3 |
Details | binding site for residue GOL A 314 |
Chain | Residue |
A | ARG110 |
A | HIS140 |
A | HIS165 |
site_id | AD6 |
Number of Residues | 5 |
Details | binding site for residue PO4 A 315 |
Chain | Residue |
A | LEU146 |
A | GLY241 |
A | TRP242 |
A | GLY243 |
A | GLN245 |
site_id | AD7 |
Number of Residues | 3 |
Details | binding site for residue PO4 A 316 |
Chain | Residue |
A | LEU198 |
A | GLY200 |
A | HOH428 |
site_id | AD8 |
Number of Residues | 2 |
Details | binding site for residue PO4 A 317 |
Chain | Residue |
A | PHE247 |
A | ASN252 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU36-ALA56 | |
A | TYR67-GLY86 | |
A | PRO113-VAL148 | |
A | LEU168-ALA188 | |
A | LEU198-MET219 | |
site_id | SWS_FT_FI2 |
Number of Residues | 28 |
Details | TOPO_DOM: Extracellular => ECO:0000305 |
Chain | Residue | Details |
A | HIS57-SER66 | |
A | THR149-THR167 | |
A | ASN220-THR221 | |
site_id | SWS_FT_FI3 |
Number of Residues | 24 |
Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
Chain | Residue | Details |
A | ARG87-GLY90 | |
A | PHE99-PHE112 | |
A | ILE189-ALA197 | |
Chain | Residue | Details |
A | ALA91-THR98 | |
A | GLY222-ILE235 | |
Chain | Residue | Details |
A | TYR135 | |