6QYI
Structure of HPAB from E.coli in complex with FAD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0010124 | biological_process | phenylacetate catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0052881 | molecular_function | 4-hydroxyphenylacetate 3-monooxygenase activity |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0010124 | biological_process | phenylacetate catabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| B | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0052881 | molecular_function | 4-hydroxyphenylacetate 3-monooxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | binding site for residue FAD A 601 |
| Chain | Residue |
| A | ARG113 |
| A | THR196 |
| A | ASP264 |
| A | THR329 |
| A | PHE332 |
| A | VAL335 |
| A | ASN396 |
| A | THR398 |
| A | SER399 |
| A | TYR457 |
| A | ASN460 |
| A | ASN154 |
| A | TYR461 |
| A | GLY463 |
| A | SER464 |
| A | ASP466 |
| A | HOH732 |
| A | HOH756 |
| A | HOH761 |
| A | HOH769 |
| A | HOH823 |
| A | HOH882 |
| A | HIS155 |
| A | HOH888 |
| A | HOH915 |
| A | HOH963 |
| B | ARG333 |
| A | ILE157 |
| A | VAL158 |
| A | ARG164 |
| A | VAL193 |
| A | VAL194 |
| A | ALA195 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue PGE A 602 |
| Chain | Residue |
| A | ASP91 |
| A | ARG94 |
| A | ARG97 |
| A | ASP354 |
| A | CYS357 |
| A | SER358 |
| B | GLU359 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue PGE A 603 |
| Chain | Residue |
| A | ARG105 |
| A | ARG346 |
| A | HOH889 |
| A | HOH933 |
| B | ASN481 |
| B | LYS484 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 604 |
| Chain | Residue |
| A | MET384 |
| A | HOH833 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 605 |
| Chain | Residue |
| A | ASP511 |
| B | THR41 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 606 |
| Chain | Residue |
| A | ASP73 |
| A | LYS88 |
| A | GLY126 |
| A | ASN365 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 607 |
| Chain | Residue |
| A | GLN54 |
| A | ASP57 |
| A | LYS61 |
| A | MET64 |
| A | HOH806 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 608 |
| Chain | Residue |
| A | LYS180 |
| B | ASP270 |
| B | GLN418 |
| B | TYR419 |
| B | LYS422 |
| B | TYR423 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 609 |
| Chain | Residue |
| A | ASP57 |
| A | HIS60 |
| A | LYS61 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 610 |
| Chain | Residue |
| A | ASP38 |
| A | LYS520 |
| A | HOH796 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 611 |
| Chain | Residue |
| A | GLU359 |
| B | ARG94 |
| B | ASP354 |
| B | CYS357 |
| B | SER358 |
| site_id | AD3 |
| Number of Residues | 34 |
| Details | binding site for residue FAD B 601 |
| Chain | Residue |
| B | PGE604 |
| B | HOH750 |
| B | HOH752 |
| B | HOH758 |
| B | HOH768 |
| B | HOH782 |
| B | HOH833 |
| B | HOH839 |
| B | HOH869 |
| B | HOH907 |
| B | HOH914 |
| A | ARG333 |
| B | ARG113 |
| B | ASN154 |
| B | HIS155 |
| B | ILE157 |
| B | VAL158 |
| B | ARG164 |
| B | VAL193 |
| B | VAL194 |
| B | ALA195 |
| B | THR196 |
| B | ASP264 |
| B | THR329 |
| B | PHE332 |
| B | VAL335 |
| B | ASN396 |
| B | THR398 |
| B | SER399 |
| B | ASN460 |
| B | TYR461 |
| B | GLY463 |
| B | SER464 |
| B | ASP466 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue EPE B 602 |
| Chain | Residue |
| B | TRP70 |
| B | ASN71 |
| B | ARG85 |
| B | SER89 |
| B | ASP92 |
| B | PGE603 |
| B | HOH761 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue PGE B 603 |
| Chain | Residue |
| B | GLN65 |
| B | ASN71 |
| B | EPE602 |
| B | HOH943 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue PGE B 604 |
| Chain | Residue |
| B | ARG164 |
| B | LEU166 |
| B | VAL213 |
| B | FAD601 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue PGE B 605 |
| Chain | Residue |
| A | ASN481 |
| A | LYS484 |
| B | ARG105 |
| B | ARG346 |
| B | HOH921 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 606 |
| Chain | Residue |
| B | ASP73 |
| B | LYS88 |
| B | GLY126 |
| B | ASN365 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 607 |
| Chain | Residue |
| B | LYS2 |
| B | GLU4 |
| B | ARG7 |
| B | GLU148 |
| B | HOH814 |
| B | HOH980 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 608 |
| Chain | Residue |
| A | THR41 |
| B | ASP511 |
| B | LEU518 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 609 |
| Chain | Residue |
| B | GLN54 |
| B | ASP57 |
| B | LYS61 |
| B | GLU63 |
| B | MET64 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 610 |
| Chain | Residue |
| B | ASP510 |
| B | ASP511 |
| B | ASN513 |
| B | MET514 |
| B | LYS517 |
