6QXV

Pink beam serial crystallography: Proteinase K, 1 us exposure, 1585 patterns merged (2 chips)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue CA A 301

Chain	Residue
A	GLU174
A	PRO175
A	VAL177
A	THR179
A	VAL198
A	ASP200
A	CL316
A	HOH401

---

site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 302

Chain	Residue
A	THR22
A	HOH406
A	HOH442
A	SER21

---

site_id	AC3
Number of Residues	7
Details	binding site for residue SO4 A 303

Chain	Residue
A	LYS242
A	TYR251
A	SER262
A	ASN263
A	HOH402
A	HOH408
A	HOH503

---

site_id	AC4
Number of Residues	5
Details	binding site for residue SO4 A 304

Chain	Residue
A	PRO7
A	TRP8
A	ARG185
A	HOH493
A	HOH494

---

site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 A 305

Chain	Residue
A	SER138
A	SER139
A	SER140
A	HOH404

---

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 A 306

Chain	Residue
A	ALA1
A	TYR25
A	ASP26
A	GLU27
A	TYR277

---

site_id	AC7
Number of Residues	6
Details	binding site for residue SO4 A 307

Chain	Residue
A	ASP184
A	SER190
A	SER191
A	THR206
A	HOH410
A	HOH421

---

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 A 308

Chain	Residue
A	ALA164
A	ASP165
A	TYR195

---

site_id	AC9
Number of Residues	5
Details	binding site for residue SO4 A 309

Chain	Residue
A	HIS69
A	ASN161
A	GLY222
A	SER224
A	HOH409

---

site_id	AD1
Number of Residues	3
Details	binding site for residue SO4 A 310

Chain	Residue
A	ARG250
A	HOH420
A	HOH475

---

site_id	AD2
Number of Residues	5
Details	binding site for residue SO4 A 311

Chain	Residue
A	SER139
A	ASP207
A	ILE220
A	SER221
A	HOH425

---

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 A 312

Chain	Residue
A	SER197
A	HOH401
A	HOH466

---

site_id	AD4
Number of Residues	4
Details	binding site for residue CA A 313

Chain	Residue
A	VAL37
A	ASP39
A	GLY41
A	VAL93

---

site_id	AD5
Number of Residues	5
Details	binding site for residue CL A 314

Chain	Residue
A	ASN257
A	GLY259
A	ASP260
A	LEU261
A	ASN270

---

site_id	AD6
Number of Residues	4
Details	binding site for residue CL A 315

Chain	Residue
A	CYS73
A	SER130
A	SER132
A	HOH458

---

site_id	AD7
Number of Residues	7
Details	binding site for residue CL A 316

Chain	Residue
A	PRO175
A	VAL177
A	ASP200
A	CA301
A	HOH401
A	HOH420
A	HOH533

---

Functional Information from PROSITE/UniProt

site_id	PS00136
Number of Residues	12
Details	SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VYVIDTGIeasH

Chain	Residue	Details
A	VAL35-HIS46

---

site_id	PS00137
Number of Residues	11
Details	SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGThCAGtVGS

Chain	Residue	Details
A	HIS69-SER79

---

site_id	PS00138
Number of Residues	11
Details	SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSmAtPhVAG

Chain	Residue	Details
A	GLY222-GLY232

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	272
Details	Domain: {"description":"Peptidase S8","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {}

Chain

Residue

Details

---