Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006259 | biological_process | DNA metabolic process |
| C | 0006265 | biological_process | DNA topological change |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 701 |
| Chain | Residue |
| B | ASP508 |
| B | ASP510 |
| B | HOH807 |
| B | HOH819 |
| B | HOH820 |
| E | HOH2214 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue JK8 B 702 |
| Chain | Residue |
| A | ARG342 |
| A | PRO343 |
| B | ARG630 |
| B | ILE633 |
| B | GLU634 |
| B | ALA637 |
| B | HOH818 |
| A | ILE30 |
| A | VAL31 |
| A | MET179 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | ASN313 |
| C | GLN257 |
| C | ALA312 |
| C | HOH617 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | PRO44 |
| A | ARG47 |
| A | ARG48 |
| A | SER158 |
| A | HOH606 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MN D 701 |
| Chain | Residue |
| D | ASP508 |
| D | ASP510 |
| D | HOH803 |
| D | HOH806 |
| D | HOH809 |
| F | HOH2113 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue JK8 D 702 |
| Chain | Residue |
| C | MET179 |
| C | ILE336 |
| C | ARG342 |
| C | PRO343 |
| C | HOH682 |
| D | ARG630 |
| D | ILE633 |
| D | GLU634 |
| D | ALA637 |
| D | TYR639 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue GLY C 501 |
| Chain | Residue |
| C | GLY226 |
| C | LEU490 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL C 502 |
| Chain | Residue |
| A | SER315 |
| A | HOH619 |
| C | SER315 |
| C | HOH617 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 503 |
| Chain | Residue |
| C | SER112 |
| C | MET113 |
| C | GLN267 |
| C | VAL268 |
| C | ASN269 |
| C | HOH620 |
| F | DC4 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL E 2101 |
| Chain | Residue |
| A | SER84 |
| E | DA7 |
| E | DG8 |
| E | DG2009 |
| E | DT2010 |
| E | HOH2215 |
Functional Information from PROSITE/UniProt
| site_id | PS00177 |
| Number of Residues | 9 |
| Details | TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG |
| Chain | Residue | Details |
| B | LEU433-GLY441 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | TYR123 | |
| C | TYR123 | |
| B | ASP510 | |
| D | GLU435 | |
| D | ASP508 | |
| D | ASP510 | |
| Chain | Residue | Details |
| B | LYS460 | |
| B | ASN463 | |
| D | LYS460 | |
| D | ASN463 | |
