6QSW

Complement factor B protease domain in complex with the reversible inhibitor N-(2-bromo-4-methylnaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine.

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0004252	molecular_function	serine-type endopeptidase activity
AAA	0005576	cellular_component	extracellular region
AAA	0006508	biological_process	proteolysis
AAA	0006956	biological_process	complement activation
BBB	0004252	molecular_function	serine-type endopeptidase activity
BBB	0005576	cellular_component	extracellular region
BBB	0006508	biological_process	proteolysis
BBB	0006956	biological_process	complement activation
CCC	0004252	molecular_function	serine-type endopeptidase activity
CCC	0005576	cellular_component	extracellular region
CCC	0006508	biological_process	proteolysis
CCC	0006956	biological_process	complement activation

Functional Information from PROSITE/UniProt

site_id	PS00134
Number of Residues	6
Details	TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC

Chain	Residue	Details
AAA	LEU53-CYS58

---

site_id	PS00135
Number of Residues	12
Details	TRYPSIN_SER Serine proteases, trypsin family, serine active site. NTcrGDSGGPLI

Chain	Residue	Details
AAA	ASN189-ILE200

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	ACT_SITE: Charge relay system

Chain	Residue	Details
AAA	HIS57
AAA	ASP102
AAA	SER195
BBB	HIS57
BBB	ASP102
BBB	SER195
CCC	HIS57
CCC	ASP102
CCC	SER195

---