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6QQR

Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0002939biological_processtRNA N1-guanine methylation
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006400biological_processtRNA modification
A0008033biological_processtRNA processing
A0008168molecular_functionmethyltransferase activity
A0016740molecular_functiontransferase activity
A0032259biological_processmethylation
A0052906molecular_functiontRNA (guanine(37)-N1)-methyltransferase activity
B0002939biological_processtRNA N1-guanine methylation
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006400biological_processtRNA modification
B0008033biological_processtRNA processing
B0008168molecular_functionmethyltransferase activity
B0016740molecular_functiontransferase activity
B0032259biological_processmethylation
B0052906molecular_functiontRNA (guanine(37)-N1)-methyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues13
Detailsbinding site for residue JDN B 301
ChainResidue
BPRO83
BGLY141
BHOH423
BHOH476
BHOH501
BTHR84
BPRO85
BGLY109
BTYR111
BTYR136
BVAL137
BLEU138
BASN139

Functional Information from PROSITE/UniProt
site_idPS00430
Number of Residues86
DetailsTONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. gsmkidvvtifpeylqpvrqslpgkaidaglvdvavhdlrrwthdvhksvddspygggpgmvmkptvwgdaldeicts.....................................ETLLVVPT
ChainResidueDetails
AGLY-1-THR84

218853

PDB entries from 2024-04-24

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