Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004129 | molecular_function | cytochrome-c oxidase activity |
| A | 0009060 | biological_process | aerobic respiration |
| A | 0016020 | cellular_component | membrane |
| A | 0020037 | molecular_function | heme binding |
| B | 0004129 | molecular_function | cytochrome-c oxidase activity |
| B | 0009060 | biological_process | aerobic respiration |
| B | 0016020 | cellular_component | membrane |
| B | 0020037 | molecular_function | heme binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue HEM A 801 |
| Chain | Residue |
| A | ALA77 |
| A | GLU407 |
| A | TYR408 |
| A | HIS631 |
| A | LEU634 |
| A | PHE635 |
| A | ARG720 |
| A | ASP724 |
| A | PHE727 |
| A | HEM802 |
| A | CA804 |
| A | TYR78 |
| A | GLN296 |
| A | VAL297 |
| A | GLY300 |
| A | TYR324 |
| A | ARG328 |
| A | HIS331 |
| A | ALA335 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | binding site for residue HEM A 802 |
| Chain | Residue |
| A | HIS75 |
| A | GLU407 |
| A | TYR408 |
| A | TRP482 |
| A | GLU490 |
| A | HIS537 |
| A | HIS538 |
| A | SER556 |
| A | GLU559 |
| A | VAL560 |
| A | LEU563 |
| A | ASN600 |
| A | ALA604 |
| A | GLY608 |
| A | ILE611 |
| A | ASN612 |
| A | THR626 |
| A | HIS629 |
| A | ALA633 |
| A | TYR638 |
| A | HEM801 |
| A | CA804 |
| A | HOH905 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue FE A 803 |
| Chain | Residue |
| A | HIS486 |
| A | HIS537 |
| A | HIS538 |
| A | HOH905 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 804 |
| Chain | Residue |
| A | GLY76 |
| A | TYR78 |
| A | GLU407 |
| A | HEM801 |
| A | HEM802 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue LOP A 805 |
| Chain | Residue |
| A | PHE680 |
| A | LEU688 |
| A | HIS692 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for residue HEM B 801 |
| Chain | Residue |
| B | ALA77 |
| B | TYR78 |
| B | GLN296 |
| B | GLY300 |
| B | TYR324 |
| B | ARG328 |
| B | HIS331 |
| B | ALA335 |
| B | GLU407 |
| B | TYR408 |
| B | HIS631 |
| B | LEU634 |
| B | PHE635 |
| B | ARG720 |
| B | ASP724 |
| B | PHE727 |
| B | HEM802 |
| B | CA804 |
| site_id | AC7 |
| Number of Residues | 23 |
| Details | binding site for residue HEM B 802 |
| Chain | Residue |
| B | HIS75 |
| B | GLU407 |
| B | TYR408 |
| B | TRP482 |
| B | GLU490 |
| B | HIS537 |
| B | HIS538 |
| B | SER556 |
| B | GLU559 |
| B | VAL560 |
| B | LEU563 |
| B | ASN600 |
| B | ALA604 |
| B | GLY608 |
| B | ILE611 |
| B | ASN612 |
| B | THR626 |
| B | HIS629 |
| B | ALA633 |
| B | TYR638 |
| B | HEM801 |
| B | CA804 |
| B | HOH906 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue FE B 803 |
| Chain | Residue |
| B | HIS486 |
| B | HIS537 |
| B | HIS538 |
| B | HOH906 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 804 |
| Chain | Residue |
| B | GLY76 |
| B | TYR78 |
| B | GLU407 |
| B | HEM801 |
| B | HEM802 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue LOP B 805 |
| Chain | Residue |
| B | TRP249 |
| B | PHE253 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue LOP B 806 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue LMT B 807 |
| Chain | Residue |
| A | HIS224 |
| A | PRO225 |
| A | SER226 |
| A | VAL230 |
| B | HIS224 |
| B | TYR619 |
| B | VAL695 |
| B | SER696 |
| B | LMT808 |
| site_id | AD4 |
| Number of Residues | 11 |
| Details | binding site for residue LMT B 808 |
| Chain | Residue |
| A | HIS224 |
| A | VAL615 |
| A | TYR619 |
| A | VAL695 |
| A | SER696 |
| B | HIS224 |
| B | PRO225 |
| B | SER226 |
| B | SER227 |
| B | VAL230 |
| B | LMT807 |
Functional Information from PROSITE/UniProt
| site_id | PS00077 |
| Number of Residues | 57 |
| Details | COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WWIVHLwVegffeafattalafifstlglvsrrmattaslasaslfmlggipgtfHH |
| Chain | Residue | Details |
| A | TRP482-HIS538 | |
