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6QOV

Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 25 (6-Phenyl-3-pyridinyl)methylamine)

Functional Information from GO Data
ChainGOidnamespacecontents
A0002939biological_processtRNA N1-guanine methylation
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006400biological_processtRNA modification
A0008033biological_processtRNA processing
A0008168molecular_functionmethyltransferase activity
A0032259biological_processmethylation
A0052906molecular_functiontRNA (guanine(37)-N1)-methyltransferase activity
B0002939biological_processtRNA N1-guanine methylation
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006400biological_processtRNA modification
B0008033biological_processtRNA processing
B0008168molecular_functionmethyltransferase activity
B0032259biological_processmethylation
B0052906molecular_functiontRNA (guanine(37)-N1)-methyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues11
Detailsbinding site for residue JAH A 301
ChainResidue
APRO83
AASN139
AGLY140
ATHR84
APRO85
AGLY109
ATYR111
ASER132
AILE133
ATYR136
ALEU138

site_idAC2
Number of Residues11
Detailsbinding site for residue JAH B 301
ChainResidue
BPRO83
BTHR84
BPRO85
BGLY109
BTYR111
BSER132
BILE133
BTYR136
BLEU138
BASN139
BGLY140

Functional Information from PROSITE/UniProt
site_idPS00430
Number of Residues86
DetailsTONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. gsmkidvvtifpeylqpvrqslpgkaidaglvdvavhdlrrwthdvhksvddspygggpgmvmkptvwgdaldeicts.....................................ETLLVVPT
ChainResidueDetails
AGLY-1-THR84

227111

PDB entries from 2024-11-06

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