6QMM
Crystal structure of Synecochoccus Spermidine Synthase in complex with putrescine, spermidine and MTA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004766 | molecular_function | spermidine synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0008295 | biological_process | spermidine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004766 | molecular_function | spermidine synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0008295 | biological_process | spermidine biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue PUT A 301 |
| Chain | Residue |
| A | MET55 |
| A | GLY160 |
| A | SER161 |
| A | GLN192 |
| A | TYR227 |
| A | TRP232 |
| A | HOH417 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue SPD B 301 |
| Chain | Residue |
| B | HIS65 |
| B | ASP89 |
| B | ASP159 |
| B | GLY160 |
| B | SER161 |
| B | ASP162 |
| B | TYR227 |
| B | TRP232 |
| B | MTA302 |
| B | HOH401 |
| B | MET55 |
| B | TYR64 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue MTA B 302 |
| Chain | Residue |
| B | GLN34 |
| B | LEU48 |
| B | LEU50 |
| B | MET55 |
| B | GLY86 |
| B | GLY88 |
| B | ASP89 |
| B | VAL108 |
| B | GLU109 |
| B | ILE110 |
| B | VAL114 |
| B | ASP140 |
| B | GLY141 |
| B | ILE142 |
| B | ASP159 |
| B | GLY160 |
| B | PRO166 |
| B | ALA167 |
| B | SPD301 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue PXN B 303 |
| Chain | Residue |
| B | PRO185 |
| B | GLY186 |
| B | ASP239 |
| B | THR240 |
| B | GLN243 |
| B | HOH434 |
| B | HOH449 |
| B | HOH474 |
Functional Information from PROSITE/UniProt
| site_id | PS01330 |
| Number of Residues | 14 |
| Details | PABS_1 Polyamine biosynthesis (PABS) domain signature. VLVIGGGdGgtVrE |
| Chain | Residue | Details |
| A | VAL82-GLU95 | |
| B | VAL82-GLU95 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30877192","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6QMM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 233 |
| Details | Domain: {"description":"PABS","evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30877192","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6QMM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
