6QM9
Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (open state)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005254 | molecular_function | chloride channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0032541 | cellular_component | cortical endoplasmic reticulum |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1902476 | biological_process | chloride transmembrane transport |
| B | 0005254 | molecular_function | chloride channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0032541 | cellular_component | cortical endoplasmic reticulum |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 1902476 | biological_process | chloride transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 801 |
| Chain | Residue |
| A | TYR188 |
| A | GLU452 |
| A | ASP503 |
| A | GLU506 |
| A | GLU535 |
| A | ASP539 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 802 |
| Chain | Residue |
| A | GLU535 |
| A | ASN448 |
| A | GLU452 |
| A | GLU506 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 801 |
| Chain | Residue |
| B | TYR188 |
| B | GLU452 |
| B | ASP503 |
| B | GLU506 |
| B | GLU535 |
| B | ASP539 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CA B 802 |
| Chain | Residue |
| B | ASN448 |
| B | GLU452 |
| B | GLU506 |
| B | GLU535 |
