Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6QLB

Calpain small subunit 1, RNA-binding protein Hfq

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
B	0005509	molecular_function	calcium ion binding
C	0005509	molecular_function	calcium ion binding
D	0005509	molecular_function	calcium ion binding
E	0003723	molecular_function	RNA binding
E	0006355	biological_process	regulation of DNA-templated transcription
F	0003723	molecular_function	RNA binding
F	0006355	biological_process	regulation of DNA-templated transcription
G	0003723	molecular_function	RNA binding
G	0006355	biological_process	regulation of DNA-templated transcription
H	0003723	molecular_function	RNA binding
H	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 201

Chain	Residue
A	ASP57
A	ASP59
A	THR61
A	LYS63
A	GLU68
A	HOH301

site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 202

Chain	Residue
A	THR93
A	GLU98
A	HOH303
A	ASP87
A	ASP89
A	SER91

site_id	AC3
Number of Residues	6
Details	binding site for residue CA A 203

Chain	Residue
A	ASP42
A	ASP130
A	ASP132
A	ASN133
A	HOH311
A	HOH325

site_id	AC4
Number of Residues	6
Details	binding site for residue CA A 204

Chain	Residue
A	ALA14
A	ASP17
A	GLU19
A	GLU24
A	HOH309
A	HOH318

site_id	AC5
Number of Residues	6
Details	binding site for residue CA A 205

Chain	Residue
A	ASP152
A	ASN154
A	THR156
A	GLN158
A	HOH324
A	HOH329

site_id	AC6
Number of Residues	11
Details	binding site for residue GUN A 206

Chain	Residue
A	ASN154
A	GLY155
A	THR156
A	HOH304
G	TYR22
G	SER57
G	THR58
G	VAL60
H	LEU23
H	LEU29
H	GLN49

site_id	AC7
Number of Residues	5
Details	binding site for residue EDO A 207

Chain	Residue
A	ARG120
A	ARG121
B	ALA54
B	ASP57
B	GLY62

site_id	AC8
Number of Residues	6
Details	binding site for residue CA B 201

Chain	Residue
B	ALA14
B	ASP17
B	GLU19
B	GLU24
B	HOH316
B	HOH324

site_id	AC9
Number of Residues	6
Details	binding site for residue CA B 202

Chain	Residue
B	ASP57
B	ASP59
B	THR61
B	LYS63
B	GLU68
B	HOH301

site_id	AD1
Number of Residues	6
Details	binding site for residue CA B 203

Chain	Residue
B	ASP87
B	ASP89
B	SER91
B	THR93
B	GLU98
B	HOH310

site_id	AD2
Number of Residues	6
Details	binding site for residue CA B 204

Chain	Residue
A	HOH313
B	ASP42
B	ASP130
B	ASP132
B	ASN133
B	HOH325

site_id	AD3
Number of Residues	5
Details	binding site for residue CA B 205

Chain	Residue
B	ASP152
B	ASN154
B	THR156
B	GLN158
B	HOH338

site_id	AD4
Number of Residues	1
Details	binding site for residue P4G B 206

Chain	Residue
B	ASP59

site_id	AD5
Number of Residues	6
Details	binding site for residue CA C 202

Chain	Residue
C	ALA14
C	ASP17
C	GLU19
C	GLU24
C	HOH307
C	HOH311

site_id	AD6
Number of Residues	6
Details	binding site for residue CA C 203

Chain	Residue
C	ASP42
C	ASP130
C	ASP132
C	ASN133
C	HOH324
D	HOH301

site_id	AD7
Number of Residues	6
Details	binding site for residue CA C 204

Chain	Residue
C	ASP57
C	ASP59
C	THR61
C	LYS63
C	GLU68
C	HOH310

site_id	AD8
Number of Residues	6
Details	binding site for residue CA C 205

Chain	Residue
C	HOH305
C	ASP87
C	ASP89
C	SER91
C	THR93
C	GLU98

site_id	AD9
Number of Residues	6
Details	binding site for residue CA C 206

Chain	Residue
C	ASP152
C	ASN154
C	THR156
C	GLN158
C	HOH325
C	HOH326

site_id	AE1
Number of Residues	5
Details	binding site for residue CA D 201

Chain	Residue
D	ALA14
D	ASP17
D	GLU19
D	GLU24
D	HOH304

site_id	AE2
Number of Residues	6
Details	binding site for residue CA D 202

Chain	Residue
D	ASP42
D	ASP130
D	ASP132
D	ASN133
D	HOH314
D	HOH316

site_id	AE3
Number of Residues	5
Details	binding site for residue CA D 203

Chain	Residue
D	ASP57
D	ASP59
D	THR61
D	LYS63
D	GLU68

site_id	AE4
Number of Residues	6
Details	binding site for residue CA D 204

Chain	Residue
D	ASP87
D	ASP89
D	SER91
D	THR93
D	GLU98
D	HOH306

site_id	AE5
Number of Residues	6
Details	binding site for residue CA D 205

Chain	Residue
D	ASP152
D	ASN154
D	THR156
D	GLN158
D	HOH319
D	HOH320

site_id	AE6
Number of Residues	11
Details	binding site for residue GUN E 101

Chain	Residue
C	ASN154
C	GLY155
C	THR156
E	TYR22
E	SER57
E	THR58
E	VAL60
E	HOH203
F	LEU23
F	GLN49
F	HOH203

site_id	AE7
Number of Residues	12
Details	binding site for residue GUN F 101

Chain	Residue
B	ASN154
B	GLY155
B	THR156
E	LEU23
E	ILE27
E	LEU29
E	GLN49
F	TYR22
F	SER57
F	THR58
F	HOH201
F	HOH202

site_id	AE8
Number of Residues	11
Details	binding site for residue GUN H 101

Chain	Residue
D	ASN154
D	GLY155
D	THR156
G	LEU23
G	ILE27
G	LEU29
G	GLN49
G	HOH104
H	TYR22
H	SER57
H	THR58

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DSDTTGKLGfeEF

Chain	Residue	Details
A	ASP57-PHE69
A	ASP87-LEU99

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q64537

Chain	Residue	Details
A	ALA14
B	GLU24
B	ASP42
B	ASP130
C	ALA14
C	ASP17
C	GLU19
C	GLU24
C	ASP42
C	ASP130
D	ALA14
A	ASP17
D	ASP17
D	GLU19
D	GLU24
D	ASP42
D	ASP130
A	GLU19
A	GLU24
A	ASP42
A	ASP130
B	ALA14
B	ASP17
B	GLU19

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU00448

Chain	Residue	Details
A	ASP57
B	ASP87
B	ASP89
B	GLU98
C	ASP57
C	ASP59
C	GLU68
C	ASP87
C	ASP89
C	GLU98
D	ASP57
A	ASP59
D	ASP59
D	GLU68
D	ASP87
D	ASP89
D	GLU98
A	GLU68
A	ASP87
A	ASP89
A	GLU98
B	ASP57
B	ASP59
B	GLU68

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q64537, ECO:0000255\|PROSITE-ProRule:PRU00448

Chain	Residue	Details
A	THR61
C	LYS63
C	SER91
C	THR93
D	THR61
D	LYS63
D	SER91
D	THR93
A	LYS63
A	SER91
A	THR93
B	THR61
B	LYS63
B	SER91
B	THR93
C	THR61

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0007744\|PubMed:19608861

Chain	Residue	Details
A	LYS84
B	LYS84
C	LYS84
D	LYS84

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)