Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH407 |
| A | HOH424 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | VAL76 |
| A | HIS91 |
| A | PRO92 |
| A | HOH413 |
| A | HOH424 |
| A | ARG66 |
| A | ILE73 |
| A | ASN74 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | CYS128 |
| A | ALA129 |
| A | PHE181 |
| A | GLN210 |
| A | EDO306 |
| A | HOH469 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | HOH434 |
| A | HOH518 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | CYS128 |
| A | SER178 |
| A | GLN192 |
| A | LYS230 |
| A | ASN233 |
| A | J5K309 |
| A | HOH469 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | LEU163 |
| A | EDO303 |
| A | J5K309 |
| A | HOH432 |
| A | HOH469 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 307 |
| Chain | Residue |
| A | TYR20 |
| A | CYS22 |
| A | THR26 |
| A | VAL27 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue DMS A 308 |
| Chain | Residue |
| A | SER217 |
| A | GLY219 |
| A | GLN221 |
| A | CYS232 |
| A | ASN233 |
| A | TYR234 |
| A | VAL235 |
| A | SER236 |
| A | HOH531 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | binding site for residue J5K A 309 |
| Chain | Residue |
| A | HIS57 |
| A | LEU99 |
| A | CYS128 |
| A | ALA129 |
| A | SER130 |
| A | SER190 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| A | GLY219 |
| A | EDO305 |
| A | EDO306 |
| A | SO4310 |
| A | HOH412 |
| A | HOH425 |
| A | HOH493 |
| A | HOH514 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 310 |
| Chain | Residue |
| A | HIS57 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | J5K309 |
| A | HOH444 |
| A | HOH483 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {} |
