6QKY
Tryptophan synthase subunit alpha from Streptococcus pneumoniae with 3D domain swap in the core of TIM barrel
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000162 | biological_process | tryptophan biosynthetic process |
A | 0004834 | molecular_function | tryptophan synthase activity |
A | 0006568 | biological_process | tryptophan metabolic process |
A | 0016829 | molecular_function | lyase activity |
B | 0000162 | biological_process | tryptophan biosynthetic process |
B | 0004834 | molecular_function | tryptophan synthase activity |
B | 0006568 | biological_process | tryptophan metabolic process |
B | 0016829 | molecular_function | lyase activity |
C | 0000162 | biological_process | tryptophan biosynthetic process |
C | 0004834 | molecular_function | tryptophan synthase activity |
C | 0006568 | biological_process | tryptophan metabolic process |
C | 0016829 | molecular_function | lyase activity |
D | 0000162 | biological_process | tryptophan biosynthetic process |
D | 0004834 | molecular_function | tryptophan synthase activity |
D | 0006568 | biological_process | tryptophan metabolic process |
D | 0016829 | molecular_function | lyase activity |
E | 0000162 | biological_process | tryptophan biosynthetic process |
E | 0004834 | molecular_function | tryptophan synthase activity |
E | 0006568 | biological_process | tryptophan metabolic process |
E | 0016829 | molecular_function | lyase activity |
F | 0000162 | biological_process | tryptophan biosynthetic process |
F | 0004834 | molecular_function | tryptophan synthase activity |
F | 0006568 | biological_process | tryptophan metabolic process |
F | 0016829 | molecular_function | lyase activity |
G | 0000162 | biological_process | tryptophan biosynthetic process |
G | 0004834 | molecular_function | tryptophan synthase activity |
G | 0006568 | biological_process | tryptophan metabolic process |
G | 0016829 | molecular_function | lyase activity |
H | 0000162 | biological_process | tryptophan biosynthetic process |
H | 0004834 | molecular_function | tryptophan synthase activity |
H | 0006568 | biological_process | tryptophan metabolic process |
H | 0016829 | molecular_function | lyase activity |
I | 0000162 | biological_process | tryptophan biosynthetic process |
I | 0004834 | molecular_function | tryptophan synthase activity |
I | 0006568 | biological_process | tryptophan metabolic process |
I | 0016829 | molecular_function | lyase activity |
J | 0000162 | biological_process | tryptophan biosynthetic process |
J | 0004834 | molecular_function | tryptophan synthase activity |
J | 0006568 | biological_process | tryptophan metabolic process |
J | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 1 |
Details | binding site for residue GOL A 301 |
Chain | Residue |
A | LYS8 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue ACY A 302 |
Chain | Residue |
A | ASP63 |
A | MSE100 |
A | TYR175 |
B | GLU52 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue PEG B 301 |
Chain | Residue |
B | GLU38 |
B | THR39 |
B | HOH410 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue ACY B 302 |
Chain | Residue |
B | ASP63 |
B | ILE67 |
B | MSE100 |
B | TYR175 |
B | GLY233 |
C | LYS185 |
A | GLU52 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue GOL C 301 |
Chain | Residue |
C | GLU86 |
C | LYS89 |
C | ASP117 |
site_id | AC6 |
Number of Residues | 3 |
Details | binding site for residue GOL C 302 |
Chain | Residue |
C | GLU38 |
C | PHE42 |
D | HOH403 |
site_id | AC7 |
Number of Residues | 5 |
Details | binding site for residue ACY C 303 |
Chain | Residue |
C | ASP63 |
C | MSE100 |
C | TYR175 |
C | GLY233 |
D | GLU52 |
site_id | AC8 |
Number of Residues | 3 |
Details | binding site for residue ACY D 301 |
Chain | Residue |
C | GLU52 |
D | ASP63 |
D | TYR175 |
site_id | AC9 |
Number of Residues | 1 |
Details | binding site for residue PEG E 301 |
Chain | Residue |
E | LYS116 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue ACY E 302 |
Chain | Residue |
E | ILE67 |
E | MSE100 |
E | TYR175 |
F | GLU52 |
site_id | AD2 |
Number of Residues | 3 |
Details | binding site for residue ACY E 303 |
Chain | Residue |
E | GLU52 |
F | ILE67 |
F | TYR175 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue ACY G 301 |
Chain | Residue |
G | MSE100 |
G | TYR175 |
G | HOH408 |
H | GLU52 |
site_id | AD4 |
Number of Residues | 4 |
Details | binding site for residue ACY H 301 |
Chain | Residue |
G | GLU52 |
H | ASP63 |
H | TYR175 |
H | GLY233 |
site_id | AD5 |
Number of Residues | 4 |
Details | binding site for residue ACY I 301 |
Chain | Residue |
I | ASP63 |
I | MSE100 |
I | TYR175 |
J | GLU52 |
site_id | AD6 |
Number of Residues | 5 |
Details | binding site for residue ACY J 301 |
Chain | Residue |
I | GLU52 |
J | ILE67 |
J | MSE100 |
J | TYR175 |
J | HOH420 |
Functional Information from PROSITE/UniProt
site_id | PS00167 |
Number of Residues | 14 |
Details | TRP_SYNTHASE_ALPHA Tryptophan synthase alpha chain signature. IEVGiPFSDPVADG |
Chain | Residue | Details |
A | ILE51-GLY64 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 20 |
Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00131 |
Chain | Residue | Details |
A | GLU52 | |
E | ASP63 | |
F | GLU52 | |
F | ASP63 | |
G | GLU52 | |
G | ASP63 | |
H | GLU52 | |
H | ASP63 | |
I | GLU52 | |
I | ASP63 | |
J | GLU52 | |
A | ASP63 | |
J | ASP63 | |
B | GLU52 | |
B | ASP63 | |
C | GLU52 | |
C | ASP63 | |
D | GLU52 | |
D | ASP63 | |
E | GLU52 |