6QI0

Time resolved structural analysis of the full turnover of an enzyme - 9024 ms

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016787	molecular_function	hydrolase activity
A	0018785	molecular_function	haloacetate dehalogenase activity
B	0003824	molecular_function	catalytic activity
B	0016787	molecular_function	hydrolase activity
B	0018785	molecular_function	haloacetate dehalogenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue FAH A 401

Chain	Residue
A	ASP110
A	ARG111
A	ARG114
A	ILE135
A	HIS155
A	TRP156
A	TYR219
A	HOH508

---

site_id	AC2
Number of Residues	6
Details	binding site for residue GOA B 401

Chain	Residue
B	ARG111
B	ARG114
B	HIS155
B	TRP156
B	TYR219
B	ASP110

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CA B 402

Chain	Residue
A	HOH584
A	HOH620
B	ASP173

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	238
Details	Domain: {"description":"AB hydrolase-1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3R3V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Site: {"description":"Important for enzyme activity","evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---