6Q7A

RORCVAR2 (RORGT, 264-499) IN COMPLEX WITH COMPOUND 4 AT 2.2A: Identification of N-aryl imidazoles as potent and selective RORgt inhibitors

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue HKZ A 501

Chain	Residue
A	TRP317
A	ILE400
A	HIS479
A	LEU483
A	CYS320
A	HIS323
A	LEU324
A	VAL361
A	LEU362
A	VAL376
A	PHE378
A	PHE388

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