6Q70
Crystal structure of the alanine racemase Bsu17640 from Bacillus subtilis in the presence of HEPES
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0008784 | molecular_function | alanine racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030632 | biological_process | D-alanine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue PLP A 401 |
| Chain | Residue |
| A | VAL37 |
| A | GLY227 |
| A | ILE228 |
| A | TYR364 |
| A | HOH503 |
| A | HOH517 |
| B | HOH517 |
| A | LYS39 |
| A | TYR43 |
| A | LEU85 |
| A | ARG139 |
| A | HIS169 |
| A | ASN209 |
| A | THR210 |
| A | ARG225 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 402 |
| Chain | Residue |
| A | ASN132 |
| A | ARG139 |
| A | HOH561 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | ARG372 |
| B | ARG372 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 404 |
| Chain | Residue |
| A | HOH542 |
| A | HOH661 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 402 |
| Chain | Residue |
| B | ASN132 |
| B | ARG139 |
| site_id | AC6 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide PLP B 401 and LYS B 39 |
| Chain | Residue |
| A | MET320 |
| A | ASP321 |
| B | VAL37 |
| B | VAL38 |
| B | ALA40 |
| B | ASN41 |
| B | GLY42 |
| B | TYR43 |
| B | ALA63 |
| B | ALA65 |
| B | GLU69 |
| B | LEU85 |
| B | ARG139 |
| B | HIS169 |
| B | ASN209 |
| B | THR210 |
| B | ARG225 |
| B | GLY227 |
| B | ILE228 |
| B | TYR364 |
| B | HOH502 |
| B | HOH553 |
| B | HOH557 |
Functional Information from PROSITE/UniProt
| site_id | PS00395 |
| Number of Residues | 11 |
| Details | ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AVvKANGYGHG |
| Chain | Residue | Details |
| A | ALA36-GLY46 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor; specific for D-alanine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor; specific for L-alanine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
