6Q5N

Crystal structure of a CC-Hex mutant that forms a parallel six-helix coiled coil CC-Hex*-L24Nle

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue GOL A 101

Chain	Residue
D	GOL101
E	ILE6

---

site_id	AC2
Number of Residues	4
Details	binding site for residue GOL B 101

Chain	Residue
A	NLE24
B	NLE24
D	NLE24
F	NLE24

---

site_id	AC3
Number of Residues	2
Details	binding site for residue GOL B 102

Chain	Residue
B	LYS18
D	ALA26

---

site_id	AC4
Number of Residues	2
Details	binding site for residue GOL C 101

Chain	Residue
E	NLE24
C	NLE24

---

site_id	AC5
Number of Residues	1
Details	binding site for residue GOL D 101

Chain	Residue
A	GOL101

---

site_id	AC6
Number of Residues	1
Details	binding site for residue GOL D 102

Chain	Residue
D	LEU3

---

site_id	AC7
Number of Residues	6
Details	binding site for residue GOL F 101

Chain	Residue
F	LYS25
F	GLN29
I	LYS25
I	GLN29
K	LYS25
K	GLN29

---

site_id	AC8
Number of Residues	4
Details	binding site for residue DIO G 101

Chain	Residue
B	LYS25
B	GLY30
D	GLN29
G	LYS25

---

site_id	AC9
Number of Residues	1
Details	binding site for residue GOL H 101

Chain	Residue
K	ILE6

---

site_id	AD1
Number of Residues	1
Details	binding site for residue GOL I 101

Chain	Residue
I	ILE13

---

site_id	AD2
Number of Residues	9
Details	binding site for Di-peptide ACE B 0 and GLY B 1

Chain	Residue
A	GLU2
B	GLU2
B	LEU3
B	LYS4
B	ALA5
B	HOH204
K	GLU2
L	ACE0
L	GLY1

---

site_id	AD3
Number of Residues	12
Details	binding site for Di-peptide GLU B 23 and NLE B 24

Chain	Residue
A	NLE24
B	ALA19
B	ILE20
B	ALA21
B	TRP22
B	LYS25
B	ALA26
B	ILE27
B	ALA28
B	GOL101
B	HOH205
C	NLE24

---

site_id	AD4
Number of Residues	15
Details	binding site for Di-peptide NLE B 24 and LYS B 25

Chain	Residue
A	GLU23
A	NLE24
B	ILE20
B	ALA21
B	TRP22
B	GLU23
B	ALA26
B	ILE27
B	ALA28
B	GLN29
B	GLY30
B	GOL101
C	NLE24
D	TRP22
G	DIO101

---

site_id	AD5
Number of Residues	8
Details	binding site for Di-peptide ACE C 0 and GLY C 1

Chain	Residue
B	GLU2
C	GLU2
C	LEU3
C	LYS4
C	ALA5
J	GLU2
K	ACE0
K	GLY1

---

site_id	AD6
Number of Residues	13
Details	binding site for Di-peptide GLU C 23 and NLE C 24

Chain	Residue
B	NLE24
C	ALA19
C	ILE20
C	ALA21
C	TRP22
C	LYS25
C	ALA26
C	ILE27
C	ALA28
C	GOL101
D	ALA21
D	NLE24
D	LYS25

---

site_id	AD7
Number of Residues	11
Details	binding site for Di-peptide NLE C 24 and LYS C 25

Chain	Residue
B	NLE24
C	ILE20
C	ALA21
C	TRP22
C	GLU23
C	ALA26
C	ILE27
C	ALA28
C	GLN29
C	GOL101
L	GLN29

---

site_id	AD8
Number of Residues	8
Details	binding site for Di-peptide ACE D 0 and GLY D 1

Chain	Residue
J	GLY1
C	GLU2
D	GLU2
D	LEU3
D	LYS4
D	ALA5
I	GLU2
J	ACE0

---

site_id	AD9
Number of Residues	13
Details	binding site for Di-peptide GLU D 23 and NLE D 24

Chain	Residue
B	GOL101
C	ILE20
C	GLU23
D	ALA19
D	ILE20
D	ALA21
D	TRP22
D	LYS25
D	ALA26
D	ILE27
D	ALA28
E	NLE24
E	LYS25

---

site_id	AE1
Number of Residues	13
Details	binding site for Di-peptide NLE D 24 and LYS D 25

Chain	Residue
B	GLY30
B	GOL101
C	ILE20
C	GLU23
D	ILE20
D	ALA21
D	TRP22
D	GLU23
D	ALA26
D	ILE27
D	ALA28
D	GLN29
E	NLE24

---

site_id	AE2
Number of Residues	8
Details	binding site for Di-peptide ACE E 0 and GLY E 1

Chain	Residue
D	GLU2
E	GLU2
E	LEU3
E	LYS4
E	ALA5
H	GLU2
I	ACE0
I	GLY1

---

site_id	AE3
Number of Residues	13
Details	binding site for Di-peptide GLU E 23 and NLE E 24

Chain	Residue
C	GOL101
D	NLE24
D	ILE27
E	ALA19
E	ILE20
E	ALA21
E	TRP22
E	LYS25
E	ALA26
E	ILE27
E	ALA28
F	NLE24
F	LYS25

---

site_id	AE4
Number of Residues	14
Details	binding site for Di-peptide NLE E 24 and LYS E 25

Chain	Residue
C	GOL101
D	GLU23
D	NLE24
D	ILE27
E	ILE20
E	ALA21
E	TRP22
E	GLU23
E	ALA26
E	ILE27
E	ALA28
E	GLN29
E	HOH105
F	NLE24

---

site_id	AE5
Number of Residues	9
Details	binding site for Di-peptide ACE F 0 and GLY F 1

Chain	Residue
E	GLU2
F	GLU2
F	LEU3
F	LYS4
F	ALA5
F	HOH207
G	GLU2
H	ACE0
H	GLY1

---

site_id	AE6
Number of Residues	14
Details	binding site for Di-peptide GLU F 23 and NLE F 24

Chain	Residue
A	NLE24
A	LYS25
B	GOL101
E	ILE20
E	NLE24
F	ALA19
F	ILE20
F	ALA21
F	TRP22
F	LYS25
F	ALA26
F	ILE27
F	ALA28
F	HOH204

---

site_id	AE7
Number of Residues	14
Details	binding site for Di-peptide NLE F 24 and LYS F 25

Chain	Residue
A	NLE24
B	GOL101
E	ILE20
E	GLU23
E	NLE24
F	ILE20
F	ALA21
F	TRP22
F	GLU23
F	ALA26
F	ILE27
F	ALA28
F	GLN29
F	GOL101

---

site_id	AE8
Number of Residues	8
Details	binding site for Di-peptide ACE G 0 and GLY G 1

Chain	Residue
A	ACE0
A	GLY1
F	GLU2
G	GLU2
G	LEU3
G	LYS4
G	ALA5
G	HOH207

---

site_id	AE9
Number of Residues	13
Details	binding site for Di-peptide GLU G 23 and NLE G 24

Chain	Residue
G	ALA19
G	ILE20
G	ALA21
G	TRP22
G	LYS25
G	ALA26
G	ILE27
G	ALA28
G	HOH201
H	NLE24
H	LYS25
L	ILE20
L	NLE24

---

site_id	AF1
Number of Residues	13
Details	binding site for Di-peptide NLE G 24 and LYS G 25

Chain	Residue
G	ILE20
G	ALA21
G	TRP22
G	GLU23
G	ALA26
G	ILE27
G	ALA28
G	GLN29
G	DIO101
H	NLE24
L	ILE20
L	GLU23
L	NLE24

---

site_id	AF2
Number of Residues	8
Details	binding site for Di-peptide ACE H 0 and GLY H 1

Chain	Residue
E	GLU2
F	ACE0
F	GLY1
G	GLU2
H	GLU2
H	LEU3
H	LYS4
H	ALA5

---

site_id	AF3
Number of Residues	14
Details	binding site for Di-peptide GLU H 23 and NLE H 24

Chain	Residue
G	ILE20
G	GLU23
G	NLE24
H	ALA19
H	ILE20
H	ALA21
H	TRP22
H	LYS25
H	ALA26
H	ILE27
H	ALA28
H	HOH201
I	NLE24
I	LYS25

---

site_id	AF4
Number of Residues	14
Details	binding site for Di-peptide NLE H 24 and LYS H 25

Chain	Residue
A	GLY30
G	ILE20
G	GLU23
G	NLE24
H	ILE20
H	ALA21
H	TRP22
H	GLU23
H	ALA26
H	ILE27
H	ALA28
H	GLN29
I	NLE24
J	TRP22

---

site_id	AF5
Number of Residues	8
Details	binding site for Di-peptide ACE I 0 and GLY I 1

Chain	Residue
D	GLU2
E	ACE0
E	GLY1
H	GLU2
I	GLU2
I	LEU3
I	LYS4
I	ALA5

---

site_id	AF6
Number of Residues	13
Details	binding site for Di-peptide GLU I 23 and NLE I 24

Chain	Residue
H	NLE24
H	ILE27
I	ALA19
I	ILE20
I	ALA21
I	TRP22
I	LYS25
I	ALA26
I	ILE27
I	ALA28
J	NLE24
J	LYS25
J	ALA28

---

site_id	AF7
Number of Residues	13
Details	binding site for Di-peptide NLE I 24 and LYS I 25

Chain	Residue
F	GLN29
F	GOL101
H	GLU23
H	NLE24
H	ILE27
I	ILE20
I	ALA21
I	TRP22
I	GLU23
I	ALA26
I	ILE27
I	ALA28
I	GLN29

---

site_id	AF8
Number of Residues	9
Details	binding site for Di-peptide ACE J 0 and GLY J 1

Chain	Residue
C	GLU2
D	ACE0
D	GLY1
I	GLU2
J	GLU2
J	LEU3
J	LYS4
J	ALA5
J	HOH206

---

site_id	AF9
Number of Residues	13
Details	binding site for Di-peptide GLU J 23 and NLE J 24

Chain	Residue
I	ILE20
I	GLU23
J	ALA19
J	ILE20
J	ALA21
J	TRP22
J	LYS25
J	ALA26
J	ILE27
J	ALA28
J	HOH203
K	NLE24
K	LYS25

---

site_id	AG1
Number of Residues	12
Details	binding site for Di-peptide NLE J 24 and LYS J 25

Chain	Residue
A	GLY30
I	ILE20
I	GLU23
J	ILE20
J	ALA21
J	TRP22
J	GLU23
J	ALA26
J	ILE27
J	ALA28
J	GLN29
K	NLE24

---

site_id	AG2
Number of Residues	8
Details	binding site for Di-peptide ACE K 0 and GLY K 1

Chain	Residue
B	GLU2
C	ACE0
C	GLY1
J	GLU2
K	GLU2
K	LEU3
K	LYS4
K	ALA5

---

site_id	AG3
Number of Residues	13
Details	binding site for Di-peptide GLU K 23 and NLE K 24

Chain	Residue
J	ILE20
J	NLE24
K	ALA19
K	ILE20
K	ALA21
K	TRP22
K	LYS25
K	ALA26
K	ILE27
K	ALA28
K	HOH101
L	NLE24
L	LYS25

---

site_id	AG4
Number of Residues	15
Details	binding site for Di-peptide NLE K 24 and LYS K 25

Chain	Residue
F	GOL101
J	ILE20
J	GLU23
J	NLE24
K	ILE20
K	ALA21
K	TRP22
K	GLU23
K	ALA26
K	ILE27
K	ALA28
K	GLN29
K	HOH104
K	HOH106
L	NLE24

---

site_id	AG5
Number of Residues	8
Details	binding site for Di-peptide ACE L 0 and GLY L 1

Chain	Residue
A	GLU2
B	ACE0
B	GLY1
K	GLU2
L	GLU2
L	LEU3
L	LYS4
L	ALA5

---

site_id	AG6
Number of Residues	12
Details	binding site for Di-peptide GLU L 23 and NLE L 24

Chain	Residue
G	NLE24
G	LYS25
K	NLE24
L	ALA19
L	ILE20
L	ALA21
L	TRP22
L	LYS25
L	ALA26
L	ILE27
L	ALA28
L	HOH202

---

site_id	AG7
Number of Residues	12
Details	binding site for Di-peptide NLE L 24 and LYS L 25

Chain	Residue
G	NLE24
K	GLU23
K	NLE24
L	ILE20
L	ALA21
L	TRP22
L	GLU23
L	ALA26
L	ILE27
L	ALA28
L	GLN29
L	HOH205

---