Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | ARG217 |
| A | PHE220 |
| A | PRO221 |
| A | LYS222 |
| A | TRP224 |
| A | VAL226 |
| B | ALA108 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| B | ARG105 |
| A | ASP213 |
| A | ARG217 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | THR232 |
| A | CYS233 |
| A | ALA234 |
| A | HD5404 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue HD5 A 404 |
| Chain | Residue |
| A | CYS63 |
| A | SER64 |
| A | LYS67 |
| A | GLU98 |
| A | TRP99 |
| A | ASN127 |
| A | GLU161 |
| A | PRO162 |
| A | SER165 |
| A | GLY231 |
| A | THR232 |
| A | EDO403 |
| A | DMS405 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue DMS A 405 |
| Chain | Residue |
| A | SER64 |
| A | SER125 |
| A | THR211 |
| A | LYS229 |
| A | THR230 |
| A | GLY231 |
| A | THR232 |
| A | ARG238 |
| A | HD5404 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | THR113 |
| A | GLU116 |
| A | HOH606 |
| B | ARG204 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 407 |
| Chain | Residue |
| A | ALA36 |
| A | GLN38 |
| A | ARG135 |
| A | GLU136 |
| A | HOH509 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 408 |
| Chain | Residue |
| A | ARG59 |
| A | ASN167 |
| A | THR168 |
| A | PRO169 |
| A | GLY170 |
| A | ASP171 |
| A | HOH519 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 409 |
| Chain | Residue |
| A | GLN145 |
| A | LYS149 |
| B | GLY81 |
| B | GLU83 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 410 |
| Chain | Residue |
| A | GLY81 |
| A | GLU83 |
| A | ARG84 |
| B | LEU22 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 411 |
| Chain | Residue |
| A | ALA141 |
| A | THR144 |
| A | LEU157 |
| A | ASP158 |
| A | HOH575 |
| B | GLU248 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 412 |
| Chain | Residue |
| A | PHE75 |
| A | ILE78 |
| A | LEU115 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 413 |
| Chain | Residue |
| A | LYS222 |
| B | PRO93 |
| B | HOH496 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 301 |
| Chain | Residue |
| A | ALA102 |
| A | PHE106 |
| A | LEU124 |
| B | GLN123 |
| B | GLN210 |
| B | HOH448 |
| B | HOH489 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue DMS B 302 |
| Chain | Residue |
| B | SER64 |
| B | SER125 |
| B | THR211 |
| B | LYS229 |
| B | THR230 |
| B | GLY231 |
| B | THR232 |
| B | ARG238 |
| B | HD5306 |
| site_id | AD7 |
| Number of Residues | 12 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | HOH401 |
| A | GLN123 |
| A | GLY208 |
| A | GLN210 |
| A | HOH560 |
| B | ALA102 |
| B | PHE106 |
| B | GLU116 |
| B | GLN119 |
| B | ALA120 |
| B | LEU124 |
| B | EDO307 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | ARG59 |
| B | GLY170 |
| B | ASP171 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| B | THR232 |
| B | CYS233 |
| B | ALA234 |
| B | HD5306 |
| site_id | AE1 |
| Number of Residues | 11 |
| Details | binding site for residue HD5 B 306 |
| Chain | Residue |
| B | CYS63 |
| B | SER64 |
| B | GLU98 |
| B | TRP99 |
| B | ASN127 |
| B | GLU161 |
| B | SER165 |
| B | GLY231 |
| B | THR232 |
| B | DMS302 |
| B | EDO305 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| A | GLN123 |
| A | ARG204 |
| A | TRP205 |
| B | PHE106 |
| B | GLU116 |
| B | EDO303 |
