6Q11

Crystal structure of MurA from Clostridium difficile, mutation C116S, in the presence of URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	32
Details	binding site for residue EPU A 501

Chain	Residue
A	LYS22
A	LEU125
A	HIS126
A	PHE160
A	SER162
A	VAL163
A	GLY164
A	ASP304
A	VAL326
A	PHE327
A	ARG330
A	ASN23
A	ARG396
A	EDO502
A	HOH601
A	HOH602
A	HOH622
A	HOH624
A	HOH642
A	HOH655
A	HOH664
A	HOH670
A	ALA93
A	HOH673
A	HOH705
A	HOH708
A	ILE118
A	THR120
A	ARG121
A	PRO122
A	ILE123
A	ASP124

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site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 502

Chain	Residue
A	ARG92
A	ARG121
A	HIS126
A	GLY164
A	EPU501
A	HOH664

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site_id	AC3
Number of Residues	5
Details	binding site for residue EDO A 503

Chain	Residue
A	GLU187
A	GLU187
A	HIS298
A	HOH645
A	HOH646

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site_id	AC4
Number of Residues	6
Details	binding site for residue NA A 504

Chain	Residue
A	ASP347
A	ASP347
A	SER350
A	SER350
A	HOH625
A	HOH625

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Functional Information from PROSITE/UniProt

site_id	PS00430
Number of Residues	80
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. gggmmakiivkksnplkgsvkidgaknavlpiiaatllangkstlngvpnlrdvhvisdllrhvgaeveyke...........................................NTLTVDAS

Chain	Residue	Details
A	GLY-3-SER76

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