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6Q11

Crystal structure of MurA from Clostridium difficile, mutation C116S, in the presence of URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0005737cellular_componentcytoplasm
A0008360biological_processregulation of cell shape
A0008760molecular_functionUDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
A0009252biological_processpeptidoglycan biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0019277biological_processUDP-N-acetylgalactosamine biosynthetic process
A0051301biological_processcell division
A0071555biological_processcell wall organization
Functional Information from PDB Data
site_idAC1
Number of Residues32
Detailsbinding site for residue EPU A 501
ChainResidue
ALYS22
ALEU125
AHIS126
APHE160
ASER162
AVAL163
AGLY164
AASP304
AVAL326
APHE327
AARG330
AASN23
AARG396
AEDO502
AHOH601
AHOH602
AHOH622
AHOH624
AHOH642
AHOH655
AHOH664
AHOH670
AALA93
AHOH673
AHOH705
AHOH708
AILE118
ATHR120
AARG121
APRO122
AILE123
AASP124

site_idAC2
Number of Residues6
Detailsbinding site for residue EDO A 502
ChainResidue
AARG92
AARG121
AHIS126
AGLY164
AEPU501
AHOH664

site_idAC3
Number of Residues5
Detailsbinding site for residue EDO A 503
ChainResidue
AGLU187
AGLU187
AHIS298
AHOH645
AHOH646

site_idAC4
Number of Residues6
Detailsbinding site for residue NA A 504
ChainResidue
AASP347
AASP347
ASER350
ASER350
AHOH625
AHOH625

Functional Information from PROSITE/UniProt
site_idPS00430
Number of Residues80
DetailsTONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. gggmmakiivkksnplkgsvkidgaknavlpiiaatllangkstlngvpnlrdvhvisdllrhvgaeveyke...........................................NTLTVDAS
ChainResidueDetails
AGLY-3-SER76

221051

PDB entries from 2024-06-12

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