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6Q03

Crystal structure of MurA from Clostridium difficile in the presence of UDP-N-acetyl-alpha-D-muramic acid with modified Cys116 (S-[(1S)-1-carboxy-1-(phosphonooxy)ethyl]-L-cysteine)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0005737cellular_componentcytoplasm
A0008360biological_processregulation of cell shape
A0008760molecular_functionUDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
A0009252biological_processpeptidoglycan biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0019277biological_processUDP-N-acetylgalactosamine biosynthetic process
A0051301biological_processcell division
A0071555biological_processcell wall organization
Functional Information from PDB Data
site_idAC1
Number of Residues32
Detailsbinding site for residue EPZ A 501
ChainResidue
ALYS22
APHE160
ASER162
AVAL163
AGLY164
AASP304
AVAL326
APHE327
AARG330
AEDO502
AHOH615
AASN23
AHOH642
AHOH647
AHOH662
AHOH663
AHOH699
AHOH718
AHOH725
AHOH729
AHOH730
AHOH794
ATHR120
AHOH799
AHOH805
AHOH808
AARG121
APRO122
AILE123
AASP124
ALEU125
AHIS126

site_idAC2
Number of Residues7
Detailsbinding site for residue EDO A 502
ChainResidue
AARG92
AARG121
AHIS126
AGLY164
AEPZ501
AHOH699
AHOH730

Functional Information from PROSITE/UniProt
site_idPS00430
Number of Residues80
DetailsTONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. ggghmakiivkksnplkgsvkidgaknavlpiiaatllangkstlngvpnlrdvhvisdllrhvgaeveyke...........................................NTLTVDAS
ChainResidueDetails
AGLY-3-SER76

246704

PDB entries from 2025-12-24

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