6PW2

Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006275	biological_process	regulation of DNA replication
A	0006355	biological_process	regulation of DNA-templated transcription
A	0042025	cellular_component	host cell nucleus
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006275	biological_process	regulation of DNA replication
B	0006355	biological_process	regulation of DNA-templated transcription
B	0042025	cellular_component	host cell nucleus
B	0045893	biological_process	positive regulation of DNA-templated transcription
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006275	biological_process	regulation of DNA replication
C	0006355	biological_process	regulation of DNA-templated transcription
C	0042025	cellular_component	host cell nucleus
C	0045893	biological_process	positive regulation of DNA-templated transcription
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0006275	biological_process	regulation of DNA replication
D	0006355	biological_process	regulation of DNA-templated transcription
D	0042025	cellular_component	host cell nucleus
D	0045893	biological_process	positive regulation of DNA-templated transcription
I	0003677	molecular_function	DNA binding
I	0003700	molecular_function	DNA-binding transcription factor activity
I	0006275	biological_process	regulation of DNA replication
I	0006355	biological_process	regulation of DNA-templated transcription
I	0042025	cellular_component	host cell nucleus
I	0045893	biological_process	positive regulation of DNA-templated transcription
J	0003677	molecular_function	DNA binding
J	0003700	molecular_function	DNA-binding transcription factor activity
J	0006275	biological_process	regulation of DNA replication
J	0006355	biological_process	regulation of DNA-templated transcription
J	0042025	cellular_component	host cell nucleus
J	0045893	biological_process	positive regulation of DNA-templated transcription
K	0003677	molecular_function	DNA binding
K	0003700	molecular_function	DNA-binding transcription factor activity
K	0006275	biological_process	regulation of DNA replication
K	0006355	biological_process	regulation of DNA-templated transcription
K	0042025	cellular_component	host cell nucleus
K	0045893	biological_process	positive regulation of DNA-templated transcription
L	0003677	molecular_function	DNA binding
L	0003700	molecular_function	DNA-binding transcription factor activity
L	0006275	biological_process	regulation of DNA replication
L	0006355	biological_process	regulation of DNA-templated transcription
L	0042025	cellular_component	host cell nucleus
L	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"For site-specific DNA endonuclease activity","evidences":[{"source":"PubMed","id":"33482082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"36037477","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"33482082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Site: {"description":"Interaction dimer-dimer","evidences":[{"source":"PubMed","id":"31142669","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Site: {"description":"Interaction dimer-dimer. Required for episome maintenance and generation of immortalized B cells in the host","evidences":[{"source":"PubMed","id":"31142669","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33482082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---